GSM5528550

Dataset: gse182409 • Sample: T054 • Status: Pregnancy-stage cohort
◂ Prev All Donors Next ▸

Quality Control Metrics

55,839,604 Total counts Group median: 70,855,220 • 16.1%ile (↓ Low)
24,813 Detected genes Group median: 31,576 • 1.0%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 7.9%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

34.6Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 10.02
bar=donor   line=cohort median 		9.31 91.4%
CETP Lipid Metabolism 0.73
bar=donor   line=cohort median 		1.18 18.3%
SIRT6 Sirtuin Family 2.07
bar=donor   line=cohort median 		2.22 31.4%
SIRT1 Sirtuin Family 5.57
bar=donor   line=cohort median 		5.50 63.8%
SIRT3 Sirtuin Family 2.44
bar=donor   line=cohort median 		2.33 67.9%
IGF1R Insulin/IGF-1 Signaling 6.76
bar=donor   line=cohort median 		7.09 19.7%
KLOTHO Anti-aging 0.06
bar=donor   line=cohort median 		0.66 14.8%
IRS2 Insulin/IGF-1 Signaling 4.61
bar=donor   line=cohort median 		5.59 2.4%
TP53 Tumor Suppression 2.17
bar=donor   line=cohort median 		2.72 17.6%
SHC1 Signal Transduction 3.78
bar=donor   line=cohort median 		3.95 19.0%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.6 1,202,403
2 ENSG00000258486 ENSG00000258486 14.2 876,933
3 ENSG00000265150 ENSG00000265150 14.1 853,301
4 B2M ENSG00000166710 protein_coding 13.8 675,234
5 S100A9 ENSG00000163220 protein_coding 13.2 449,517
6 AL355075.4 ENSG00000259001 lncRNA 13.0 392,915
7 MALAT1 ENSG00000251562 lncRNA 13.0 380,845
8 BNIP3L ENSG00000104765 protein_coding 12.9 373,281
9 NAMPT ENSG00000105835 protein_coding 12.9 362,528
10 ALAS2 ENSG00000158578 protein_coding 12.7 311,409

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.9
bar=donor   line=cohort median 		11.8 11.8 58.6%
2 S100A9 protein_coding 13.2
bar=donor   line=cohort median 		13.1 13.1 60.6%
3 IL1B protein_coding 7.4
bar=donor   line=cohort median 		6.9 6.9 88.7%
4 CXCL8 protein_coding 8.7
bar=donor   line=cohort median 		7.6 7.6 88.0%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.2
bar=donor   line=cohort median 		4.0 4.0 57.9%
6 FCGR3B protein_coding 11.7
bar=donor   line=cohort median 		11.3 11.3 73.6%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.4
bar=donor   line=cohort median 		10.9 10.9 87.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.7
bar=donor   line=cohort median 		5.3 5.3 82.5%
9 CD3E protein_coding 1.5
bar=donor   line=cohort median 		2.6 2.6 5.1%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.0
bar=donor   line=cohort median 		6.3 6.3 28.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.4
bar=donor   line=cohort median 		3.4 3.4 5.8%
12 GNLY protein_coding 4.3
bar=donor   line=cohort median 		4.9 4.9 17.5%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 6.7
bar=donor   line=cohort median 		6.6 6.6 52.4%
14 HBA1 protein_coding 4.4
bar=donor   line=cohort median 		2.6 2.6 68.2%
15 HBA2 protein_coding 7.1
bar=donor   line=cohort median 		5.6 5.6 66.1%
◂ Previous Donor Back to Donor List Next Donor ▸