GSM5528551

Dataset: gse182409 • Sample: T055 • Status: Pregnancy-stage cohort
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Quality Control Metrics

85,321,160 Total counts Group median: 70,855,220 • 82.5%ile (↑ High)
32,454 Detected genes Group median: 31,576 • 71.6%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 29.1%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

55.3Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.14
bar=donor   line=cohort median 		9.31 36.9%
CETP Lipid Metabolism 1.80
bar=donor   line=cohort median 		1.18 84.5%
SIRT6 Sirtuin Family 2.38
bar=donor   line=cohort median 		2.22 75.5%
SIRT1 Sirtuin Family 5.93
bar=donor   line=cohort median 		5.50 99.0%
SIRT3 Sirtuin Family 2.16
bar=donor   line=cohort median 		2.33 23.1%
IGF1R Insulin/IGF-1 Signaling 6.70
bar=donor   line=cohort median 		7.09 16.2%
KLOTHO Anti-aging 1.40
bar=donor   line=cohort median 		0.66 91.4%
IRS2 Insulin/IGF-1 Signaling 5.58
bar=donor   line=cohort median 		5.59 47.9%
TP53 Tumor Suppression 2.45
bar=donor   line=cohort median 		2.72 36.2%
SHC1 Signal Transduction 3.88
bar=donor   line=cohort median 		3.95 42.4%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.9 4,539,689
2 ENSG00000258486 ENSG00000258486 15.7 3,929,023
3 7SK ENSG00000202198 misc_RNA 15.0 2,381,199
4 AL355075.4 ENSG00000259001 lncRNA 13.6 912,934
5 B2M ENSG00000166710 protein_coding 13.4 798,442
6 MALAT1 ENSG00000251562 lncRNA 13.4 797,133
7 S100A9 ENSG00000163220 protein_coding 13.3 767,101
8 ALAS2 ENSG00000158578 protein_coding 13.1 641,404
9 NAMPT ENSG00000105835 protein_coding 12.7 494,637
10 SLC25A37 ENSG00000147454 protein_coding 12.5 428,074

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.0
bar=donor   line=cohort median 		11.8 11.8 64.7%
2 S100A9 protein_coding 13.3
bar=donor   line=cohort median 		13.1 13.1 75.0%
3 IL1B protein_coding 7.2
bar=donor   line=cohort median 		6.9 6.9 75.7%
4 CXCL8 protein_coding 7.6
bar=donor   line=cohort median 		7.6 7.6 50.3%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.7
bar=donor   line=cohort median 		4.0 4.0 40.8%
6 FCGR3B protein_coding 11.6
bar=donor   line=cohort median 		11.3 11.3 68.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.0
bar=donor   line=cohort median 		10.9 10.9 4.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.1
bar=donor   line=cohort median 		5.3 5.3 31.2%
9 CD3E protein_coding 2.2
bar=donor   line=cohort median 		2.6 2.6 27.1%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.2
bar=donor   line=cohort median 		6.3 6.3 45.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.7
bar=donor   line=cohort median 		3.4 3.4 16.8%
12 GNLY protein_coding 4.5
bar=donor   line=cohort median 		4.9 4.9 27.7%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.5
bar=donor   line=cohort median 		6.6 6.6 25.0%
14 HBA1 protein_coding 3.3
bar=donor   line=cohort median 		2.6 2.6 59.2%
15 HBA2 protein_coding 6.5
bar=donor   line=cohort median 		5.6 5.6 60.6%
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