GSM5528552

Dataset: gse182409 • Sample: T056 • Status: Pregnancy-stage cohort
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Quality Control Metrics

78,177,905 Total counts Group median: 70,855,220 • 66.1%ile (≈ Median)
28,657 Detected genes Group median: 31,576 • 22.3%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 77.7%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

48.8Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.95
bar=donor   line=cohort median 		9.31 20.3%
CETP Lipid Metabolism 1.31
bar=donor   line=cohort median 		1.18 59.7%
SIRT6 Sirtuin Family 2.31
bar=donor   line=cohort median 		2.22 65.2%
SIRT1 Sirtuin Family 5.52
bar=donor   line=cohort median 		5.50 56.2%
SIRT3 Sirtuin Family 2.49
bar=donor   line=cohort median 		2.33 73.5%
IGF1R Insulin/IGF-1 Signaling 7.14
bar=donor   line=cohort median 		7.09 54.8%
KLOTHO Anti-aging 1.29
bar=donor   line=cohort median 		0.66 87.2%
IRS2 Insulin/IGF-1 Signaling 5.62
bar=donor   line=cohort median 		5.59 54.1%
TP53 Tumor Suppression 1.96
bar=donor   line=cohort median 		2.72 8.6%
SHC1 Signal Transduction 3.64
bar=donor   line=cohort median 		3.95 7.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ALAS2 ENSG00000158578 protein_coding 14.4 1,523,390
2 7SK ENSG00000202198 misc_RNA 14.3 1,457,645
3 ENSG00000258486 ENSG00000258486 13.5 854,819
4 B2M ENSG00000166710 protein_coding 13.5 808,974
5 ENSG00000265150 ENSG00000265150 13.4 773,971
6 MALAT1 ENSG00000251562 lncRNA 13.0 604,036
7 S100A9 ENSG00000163220 protein_coding 12.9 549,936
8 ENSG00000138293 ENSG00000138293 12.8 506,559
9 SLC25A37 ENSG00000147454 protein_coding 12.8 504,363
10 AL355075.4 ENSG00000259001 lncRNA 12.7 489,015

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.7
bar=donor   line=cohort median 		11.8 11.8 41.4%
2 S100A9 protein_coding 12.9
bar=donor   line=cohort median 		13.1 13.1 38.0%
3 IL1B protein_coding 7.6
bar=donor   line=cohort median 		6.9 6.9 92.8%
4 CXCL8 protein_coding 6.8
bar=donor   line=cohort median 		7.6 7.6 25.0%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.8
bar=donor   line=cohort median 		4.0 4.0 44.2%
6 FCGR3B protein_coding 11.4
bar=donor   line=cohort median 		11.3 11.3 57.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.4
bar=donor   line=cohort median 		10.9 10.9 16.1%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 6.0
bar=donor   line=cohort median 		5.3 5.3 96.2%
9 CD3E protein_coding 2.5
bar=donor   line=cohort median 		2.6 2.6 42.1%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 7.5
bar=donor   line=cohort median 		6.3 6.3 99.7%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.6
bar=donor   line=cohort median 		3.4 3.4 12.0%
12 GNLY protein_coding 4.6
bar=donor   line=cohort median 		4.9 4.9 31.2%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 10.0
bar=donor   line=cohort median 		6.6 6.6 88.0%
14 HBA1 protein_coding 5.7
bar=donor   line=cohort median 		2.6 2.6 81.8%
15 HBA2 protein_coding 8.1
bar=donor   line=cohort median 		5.6 5.6 77.1%
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