GSM5528553

Dataset: gse182409 • Sample: T057 • Status: Pregnancy-stage cohort
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Quality Control Metrics

50,819,233 Total counts Group median: 70,855,220 • 8.6%ile (↓ Low)
32,271 Detected genes Group median: 31,576 • 66.8%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 99.0%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

32.3Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.99
bar=donor   line=cohort median 		9.31 88.6%
CETP Lipid Metabolism 1.16
bar=donor   line=cohort median 		1.18 46.6%
SIRT6 Sirtuin Family 1.32
bar=donor   line=cohort median 		2.22 0.3%
SIRT1 Sirtuin Family 5.34
bar=donor   line=cohort median 		5.50 15.5%
SIRT3 Sirtuin Family 2.73
bar=donor   line=cohort median 		2.33 91.4%
IGF1R Insulin/IGF-1 Signaling 6.74
bar=donor   line=cohort median 		7.09 18.3%
KLOTHO Anti-aging -0.20
bar=donor   line=cohort median 		0.66 3.1%
IRS2 Insulin/IGF-1 Signaling 4.49
bar=donor   line=cohort median 		5.59 1.7%
TP53 Tumor Suppression 2.07
bar=donor   line=cohort median 		2.72 12.8%
SHC1 Signal Transduction 3.89
bar=donor   line=cohort median 		3.95 44.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.7 2,465,147
2 ENSG00000258486 ENSG00000258486 15.3 1,943,755
3 7SK ENSG00000202198 misc_RNA 13.7 640,988
4 ALAS2 ENSG00000158578 protein_coding 13.5 560,161
5 MALAT1 ENSG00000251562 lncRNA 13.2 456,275
6 FKBP8 ENSG00000105701 protein_coding 12.7 316,764
7 SLC25A37 ENSG00000147454 protein_coding 12.6 303,421
8 AL355075.4 ENSG00000259001 lncRNA 12.5 284,816
9 DCAF12 ENSG00000198876 protein_coding 12.5 280,256
10 S100A9 ENSG00000163220 protein_coding 12.4 255,226

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 10.9
bar=donor   line=cohort median 		11.8 11.8 3.1%
2 S100A9 protein_coding 12.4
bar=donor   line=cohort median 		13.1 13.1 7.2%
3 IL1B protein_coding 7.0
bar=donor   line=cohort median 		6.9 6.9 62.7%
4 CXCL8 protein_coding 6.7
bar=donor   line=cohort median 		7.6 7.6 20.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 2.4
bar=donor   line=cohort median 		4.0 4.0 9.2%
6 FCGR3B protein_coding 11.0
bar=donor   line=cohort median 		11.3 11.3 26.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 9.9
bar=donor   line=cohort median 		10.9 10.9 3.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 4.4
bar=donor   line=cohort median 		5.3 5.3 1.0%
9 CD3E protein_coding 3.8
bar=donor   line=cohort median 		2.6 2.6 94.9%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.5
bar=donor   line=cohort median 		6.3 6.3 3.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.5
bar=donor   line=cohort median 		3.4 3.4 92.1%
12 GNLY protein_coding 5.1
bar=donor   line=cohort median 		4.9 4.9 64.0%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 8.2
bar=donor   line=cohort median 		6.6 6.6 70.9%
14 HBA1 protein_coding 3.7
bar=donor   line=cohort median 		2.6 2.6 63.4%
15 HBA2 protein_coding 7.6
bar=donor   line=cohort median 		5.6 5.6 69.5%
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