GSM5528554

Dataset: gse182409 • Sample: T058 • Status: Pregnancy-stage cohort
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Quality Control Metrics

58,674,673 Total counts Group median: 70,855,220 • 19.5%ile (↓ Low)
27,701 Detected genes Group median: 31,576 • 12.7%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 60.6%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

79.6Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.61
bar=donor   line=cohort median 		9.31 74.8%
CETP Lipid Metabolism 2.45
bar=donor   line=cohort median 		1.18 98.3%
SIRT6 Sirtuin Family 2.48
bar=donor   line=cohort median 		2.22 86.6%
SIRT1 Sirtuin Family 5.27
bar=donor   line=cohort median 		5.50 5.2%
SIRT3 Sirtuin Family 2.58
bar=donor   line=cohort median 		2.33 84.5%
IGF1R Insulin/IGF-1 Signaling 7.70
bar=donor   line=cohort median 		7.09 97.6%
KLOTHO Anti-aging 1.11
bar=donor   line=cohort median 		0.66 78.3%
IRS2 Insulin/IGF-1 Signaling 5.87
bar=donor   line=cohort median 		5.59 76.2%
TP53 Tumor Suppression 3.79
bar=donor   line=cohort median 		2.72 96.9%
SHC1 Signal Transduction 4.51
bar=donor   line=cohort median 		3.95 97.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000258486 ENSG00000258486 13.8 720,864
2 7SK ENSG00000202198 misc_RNA 13.8 716,975
3 ENSG00000265150 ENSG00000265150 13.8 702,123
4 HBB ENSG00000244734 protein_coding 13.7 690,416
5 MALAT1 ENSG00000251562 lncRNA 13.2 473,159
6 B2M ENSG00000166710 protein_coding 13.0 429,753
7 ALAS2 ENSG00000158578 protein_coding 13.0 425,691
8 EPB41 ENSG00000159023 protein_coding 12.7 336,934
9 SLC25A37 ENSG00000147454 protein_coding 12.6 321,434
10 BNIP3L ENSG00000104765 protein_coding 12.5 298,254

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 10.9
bar=donor   line=cohort median 		11.8 11.8 3.8%
2 S100A9 protein_coding 12.2
bar=donor   line=cohort median 		13.1 13.1 3.1%
3 IL1B protein_coding 6.2
bar=donor   line=cohort median 		6.9 6.9 17.5%
4 CXCL8 protein_coding 8.3
bar=donor   line=cohort median 		7.6 7.6 77.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.7
bar=donor   line=cohort median 		4.0 4.0 42.1%
6 FCGR3B protein_coding 11.6
bar=donor   line=cohort median 		11.3 11.3 70.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.1
bar=donor   line=cohort median 		10.9 10.9 10.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.3
bar=donor   line=cohort median 		5.3 5.3 51.0%
9 CD3E protein_coding 3.4
bar=donor   line=cohort median 		2.6 2.6 86.0%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.7
bar=donor   line=cohort median 		6.3 6.3 14.0%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.9
bar=donor   line=cohort median 		3.4 3.4 96.2%
12 GNLY protein_coding 5.2
bar=donor   line=cohort median 		4.9 4.9 72.3%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 13.7
bar=donor   line=cohort median 		6.6 6.6 99.0%
14 HBA1 protein_coding 8.1
bar=donor   line=cohort median 		2.6 2.6 97.6%
15 HBA2 protein_coding 11.7
bar=donor   line=cohort median 		5.6 5.6 99.0%
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