GSM5528555

Dataset: gse182409 • Sample: T059 • Status: Pregnancy-stage cohort
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Quality Control Metrics

84,627,406 Total counts Group median: 70,855,220 • 81.8%ile (↑ High)
32,322 Detected genes Group median: 31,576 • 68.2%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 78.4%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

75.1Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.45
bar=donor   line=cohort median 		9.31 62.4%
CETP Lipid Metabolism 1.64
bar=donor   line=cohort median 		1.18 78.3%
SIRT6 Sirtuin Family 2.75
bar=donor   line=cohort median 		2.22 97.6%
SIRT1 Sirtuin Family 5.53
bar=donor   line=cohort median 		5.50 59.7%
SIRT3 Sirtuin Family 2.50
bar=donor   line=cohort median 		2.33 75.5%
IGF1R Insulin/IGF-1 Signaling 7.03
bar=donor   line=cohort median 		7.09 43.1%
KLOTHO Anti-aging 0.68
bar=donor   line=cohort median 		0.66 52.1%
IRS2 Insulin/IGF-1 Signaling 6.24
bar=donor   line=cohort median 		5.59 92.8%
TP53 Tumor Suppression 3.43
bar=donor   line=cohort median 		2.72 90.7%
SHC1 Signal Transduction 4.56
bar=donor   line=cohort median 		3.95 99.0%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.1 2,795,242
2 ENSG00000258486 ENSG00000258486 14.9 2,414,395
3 7SK ENSG00000202198 misc_RNA 14.5 1,733,960
4 B2M ENSG00000166710 protein_coding 13.4 821,740
5 MALAT1 ENSG00000251562 lncRNA 13.4 811,930
6 S100A9 ENSG00000163220 protein_coding 13.2 727,659
7 NAMPT ENSG00000105835 protein_coding 13.0 646,274
8 AL355075.4 ENSG00000259001 lncRNA 12.9 593,697
9 ALAS2 ENSG00000158578 protein_coding 12.9 568,356
10 SOD2 ENSG00000112096 protein_coding 12.5 448,732

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.8
bar=donor   line=cohort median 		11.8 11.8 46.9%
2 S100A9 protein_coding 13.2
bar=donor   line=cohort median 		13.1 13.1 59.2%
3 IL1B protein_coding 7.2
bar=donor   line=cohort median 		6.9 6.9 77.7%
4 CXCL8 protein_coding 9.3
bar=donor   line=cohort median 		7.6 7.6 96.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.5
bar=donor   line=cohort median 		4.0 4.0 89.4%
6 FCGR3B protein_coding 10.5
bar=donor   line=cohort median 		11.3 11.3 7.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.7
bar=donor   line=cohort median 		10.9 10.9 33.2%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.3
bar=donor   line=cohort median 		5.3 5.3 53.1%
9 CD3E protein_coding 2.9
bar=donor   line=cohort median 		2.6 2.6 61.3%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.7
bar=donor   line=cohort median 		6.3 6.3 9.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.4
bar=donor   line=cohort median 		3.4 3.4 88.7%
12 GNLY protein_coding 4.7
bar=donor   line=cohort median 		4.9 4.9 34.6%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 7.6
bar=donor   line=cohort median 		6.6 6.6 61.3%
14 HBA1 protein_coding 2.8
bar=donor   line=cohort median 		2.6 2.6 53.1%
15 HBA2 protein_coding 6.0
bar=donor   line=cohort median 		5.6 5.6 54.5%
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