GSM5528557

Dataset: gse182409 • Sample: T061 • Status: Pregnancy-stage cohort
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Quality Control Metrics

51,540,786 Total counts Group median: 70,855,220 • 9.9%ile (↓ Low)
32,354 Detected genes Group median: 31,576 • 68.8%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 83.9%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

59.9Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.01
bar=donor   line=cohort median 		9.31 25.2%
CETP Lipid Metabolism 1.51
bar=donor   line=cohort median 		1.18 70.7%
SIRT6 Sirtuin Family 2.36
bar=donor   line=cohort median 		2.22 70.0%
SIRT1 Sirtuin Family 5.68
bar=donor   line=cohort median 		5.50 83.8%
SIRT3 Sirtuin Family 2.21
bar=donor   line=cohort median 		2.33 28.6%
IGF1R Insulin/IGF-1 Signaling 7.34
bar=donor   line=cohort median 		7.09 76.9%
KLOTHO Anti-aging 0.11
bar=donor   line=cohort median 		0.66 18.3%
IRS2 Insulin/IGF-1 Signaling 6.30
bar=donor   line=cohort median 		5.59 94.8%
TP53 Tumor Suppression 2.75
bar=donor   line=cohort median 		2.72 54.8%
SHC1 Signal Transduction 4.14
bar=donor   line=cohort median 		3.95 75.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 13.8 758,719
2 ENSG00000258486 ENSG00000258486 13.6 681,060
3 MALAT1 ENSG00000251562 lncRNA 13.6 669,536
4 7SK ENSG00000202198 misc_RNA 13.4 575,142
5 ALAS2 ENSG00000158578 protein_coding 13.3 524,450
6 S100A9 ENSG00000163220 protein_coding 12.8 369,374
7 B2M ENSG00000166710 protein_coding 12.7 364,930
8 SLC25A37 ENSG00000147454 protein_coding 12.5 314,901
9 FCGR3B ENSG00000162747 protein_coding 12.4 281,692
10 SORL1 ENSG00000137642 protein_coding 12.2 249,324

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.3
bar=donor   line=cohort median 		11.8 11.8 15.4%
2 S100A9 protein_coding 12.8
bar=donor   line=cohort median 		13.1 13.1 27.1%
3 IL1B protein_coding 6.9
bar=donor   line=cohort median 		6.9 6.9 50.3%
4 CXCL8 protein_coding 6.4
bar=donor   line=cohort median 		7.6 7.6 15.4%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 2.9
bar=donor   line=cohort median 		4.0 4.0 22.3%
6 FCGR3B protein_coding 12.4
bar=donor   line=cohort median 		11.3 11.3 97.6%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 9.7
bar=donor   line=cohort median 		10.9 10.9 1.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 4.8
bar=donor   line=cohort median 		5.3 5.3 8.6%
9 CD3E protein_coding 3.8
bar=donor   line=cohort median 		2.6 2.6 93.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 4.9
bar=donor   line=cohort median 		6.3 6.3 0.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.1
bar=donor   line=cohort median 		3.4 3.4 82.5%
12 GNLY protein_coding 5.0
bar=donor   line=cohort median 		4.9 4.9 55.8%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.0
bar=donor   line=cohort median 		6.6 6.6 13.4%
14 HBA1 protein_coding 0.3
bar=donor   line=cohort median 		2.6 2.6 25.0%
15 HBA2 protein_coding 3.9
bar=donor   line=cohort median 		5.6 5.6 30.5%
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