GSM5528558

Dataset: gse182409 • Sample: T062 • Status: Pregnancy-stage cohort
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Quality Control Metrics

43,601,036 Total counts Group median: 70,855,220 • 3.1%ile (↓ Low)
31,647 Detected genes Group median: 31,576 • 51.0%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 10.6%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

71.5Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.81
bar=donor   line=cohort median 		9.31 84.5%
CETP Lipid Metabolism 2.63
bar=donor   line=cohort median 		1.18 99.7%
SIRT6 Sirtuin Family 2.22
bar=donor   line=cohort median 		2.22 50.0%
SIRT1 Sirtuin Family 5.31
bar=donor   line=cohort median 		5.50 10.0%
SIRT3 Sirtuin Family 2.41
bar=donor   line=cohort median 		2.33 63.1%
IGF1R Insulin/IGF-1 Signaling 7.73
bar=donor   line=cohort median 		7.09 98.3%
KLOTHO Anti-aging 1.03
bar=donor   line=cohort median 		0.66 72.1%
IRS2 Insulin/IGF-1 Signaling 5.85
bar=donor   line=cohort median 		5.59 72.1%
TP53 Tumor Suppression 3.21
bar=donor   line=cohort median 		2.72 79.7%
SHC1 Signal Transduction 4.23
bar=donor   line=cohort median 		3.95 85.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.9 1,237,178
2 ENSG00000258486 ENSG00000258486 14.7 1,084,972
3 7SK ENSG00000202198 misc_RNA 14.4 859,950
4 MALAT1 ENSG00000251562 lncRNA 13.6 492,489
5 AL355075.4 ENSG00000259001 lncRNA 13.3 410,311
6 B2M ENSG00000166710 protein_coding 13.2 389,551
7 BNIP3L ENSG00000104765 protein_coding 12.9 319,597
8 S100A9 ENSG00000163220 protein_coding 12.8 288,722
9 ALAS2 ENSG00000158578 protein_coding 12.6 247,935
10 SLC25A37 ENSG00000147454 protein_coding 12.3 207,595

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.6
bar=donor   line=cohort median 		11.8 11.8 36.6%
2 S100A9 protein_coding 12.8
bar=donor   line=cohort median 		13.1 13.1 29.1%
3 IL1B protein_coding 6.5
bar=donor   line=cohort median 		6.9 6.9 26.4%
4 CXCL8 protein_coding 7.4
bar=donor   line=cohort median 		7.6 7.6 44.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.2
bar=donor   line=cohort median 		4.0 4.0 83.2%
6 FCGR3B protein_coding 11.3
bar=donor   line=cohort median 		11.3 11.3 50.3%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.9
bar=donor   line=cohort median 		10.9 10.9 51.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.2
bar=donor   line=cohort median 		5.3 5.3 38.0%
9 CD3E protein_coding 3.1
bar=donor   line=cohort median 		2.6 2.6 72.3%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.4
bar=donor   line=cohort median 		6.3 6.3 59.2%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.3
bar=donor   line=cohort median 		3.4 3.4 46.9%
12 GNLY protein_coding 4.7
bar=donor   line=cohort median 		4.9 4.9 36.0%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.5
bar=donor   line=cohort median 		6.6 6.6 24.3%
14 HBA1 protein_coding 0.4
bar=donor   line=cohort median 		2.6 2.6 25.7%
15 HBA2 protein_coding 3.9
bar=donor   line=cohort median 		5.6 5.6 32.5%
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