GSM5528559

Dataset: gse182409 • Sample: T063 • Status: Pregnancy-stage cohort
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Quality Control Metrics

78,324,389 Total counts Group median: 70,855,220 • 66.8%ile (≈ Median)
33,473 Detected genes Group median: 31,576 • 90.1%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 69.5%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

43.4Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.22
bar=donor   line=cohort median 		9.31 45.2%
CETP Lipid Metabolism 0.84
bar=donor   line=cohort median 		1.18 23.8%
SIRT6 Sirtuin Family 1.84
bar=donor   line=cohort median 		2.22 10.7%
SIRT1 Sirtuin Family 5.64
bar=donor   line=cohort median 		5.50 78.3%
SIRT3 Sirtuin Family 2.05
bar=donor   line=cohort median 		2.33 12.1%
IGF1R Insulin/IGF-1 Signaling 7.19
bar=donor   line=cohort median 		7.09 60.3%
KLOTHO Anti-aging 1.37
bar=donor   line=cohort median 		0.66 89.3%
IRS2 Insulin/IGF-1 Signaling 5.46
bar=donor   line=cohort median 		5.59 36.9%
TP53 Tumor Suppression 2.80
bar=donor   line=cohort median 		2.72 57.6%
SHC1 Signal Transduction 3.79
bar=donor   line=cohort median 		3.95 19.7%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.2 2,870,296
2 ENSG00000258486 ENSG00000258486 15.1 2,727,888
3 7SK ENSG00000202198 misc_RNA 14.4 1,675,225
4 MALAT1 ENSG00000251562 lncRNA 13.3 768,447
5 ALAS2 ENSG00000158578 protein_coding 13.3 745,317
6 B2M ENSG00000166710 protein_coding 13.1 671,981
7 AL355075.4 ENSG00000259001 lncRNA 12.8 554,927
8 S100A9 ENSG00000163220 protein_coding 12.7 508,440
9 SLC25A37 ENSG00000147454 protein_coding 12.6 465,030
10 EPB41 ENSG00000159023 protein_coding 12.2 367,322

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.3
bar=donor   line=cohort median 		11.8 11.8 16.1%
2 S100A9 protein_coding 12.7
bar=donor   line=cohort median 		13.1 13.1 21.6%
3 IL1B protein_coding 6.6
bar=donor   line=cohort median 		6.9 6.9 37.3%
4 CXCL8 protein_coding 8.0
bar=donor   line=cohort median 		7.6 7.6 66.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.5
bar=donor   line=cohort median 		4.0 4.0 65.4%
6 FCGR3B protein_coding 11.1
bar=donor   line=cohort median 		11.3 11.3 31.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.5
bar=donor   line=cohort median 		10.9 10.9 22.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.1
bar=donor   line=cohort median 		5.3 5.3 25.0%
9 CD3E protein_coding 3.1
bar=donor   line=cohort median 		2.6 2.6 73.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.7
bar=donor   line=cohort median 		6.3 6.3 12.7%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.8
bar=donor   line=cohort median 		3.4 3.4 68.2%
12 GNLY protein_coding 5.1
bar=donor   line=cohort median 		4.9 4.9 65.4%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 6.8
bar=donor   line=cohort median 		6.6 6.6 53.1%
14 HBA1 protein_coding 1.6
bar=donor   line=cohort median 		2.6 2.6 37.3%
15 HBA2 protein_coding 5.2
bar=donor   line=cohort median 		5.6 5.6 43.5%
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