GSM5528560

Dataset: gse182409 • Sample: T064 • Status: Pregnancy-stage cohort
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Quality Control Metrics

85,332,488 Total counts Group median: 70,855,220 • 83.2%ile (↑ High)
28,919 Detected genes Group median: 31,576 • 25.7%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 8.6%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

58.7Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.41
bar=donor   line=cohort median 		9.31 59.0%
CETP Lipid Metabolism 1.82
bar=donor   line=cohort median 		1.18 85.9%
SIRT6 Sirtuin Family 2.06
bar=donor   line=cohort median 		2.22 30.0%
SIRT1 Sirtuin Family 5.43
bar=donor   line=cohort median 		5.50 30.7%
SIRT3 Sirtuin Family 2.27
bar=donor   line=cohort median 		2.33 44.5%
IGF1R Insulin/IGF-1 Signaling 7.21
bar=donor   line=cohort median 		7.09 65.2%
KLOTHO Anti-aging 0.88
bar=donor   line=cohort median 		0.66 65.2%
IRS2 Insulin/IGF-1 Signaling 5.41
bar=donor   line=cohort median 		5.59 32.8%
TP53 Tumor Suppression 3.31
bar=donor   line=cohort median 		2.72 84.5%
SHC1 Signal Transduction 4.25
bar=donor   line=cohort median 		3.95 89.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.9 2,501,671
2 ENSG00000258486 ENSG00000258486 14.6 2,044,984
3 ENSG00000265150 ENSG00000265150 14.5 1,910,019
4 AL355075.4 ENSG00000259001 lncRNA 13.5 978,518
5 B2M ENSG00000166710 protein_coding 13.4 917,147
6 MALAT1 ENSG00000251562 lncRNA 13.1 723,241
7 ALAS2 ENSG00000158578 protein_coding 13.0 686,629
8 BNIP3L ENSG00000104765 protein_coding 12.8 570,533
9 S100A9 ENSG00000163220 protein_coding 12.7 557,439
10 SLC25A37 ENSG00000147454 protein_coding 12.7 537,687

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.4
bar=donor   line=cohort median 		11.8 11.8 22.3%
2 S100A9 protein_coding 12.7
bar=donor   line=cohort median 		13.1 13.1 24.3%
3 IL1B protein_coding 6.7
bar=donor   line=cohort median 		6.9 6.9 38.7%
4 CXCL8 protein_coding 7.3
bar=donor   line=cohort median 		7.6 7.6 42.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.9
bar=donor   line=cohort median 		4.0 4.0 46.2%
6 FCGR3B protein_coding 10.8
bar=donor   line=cohort median 		11.3 11.3 13.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.2
bar=donor   line=cohort median 		10.9 10.9 75.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.8
bar=donor   line=cohort median 		5.3 5.3 92.1%
9 CD3E protein_coding 2.2
bar=donor   line=cohort median 		2.6 2.6 32.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.4
bar=donor   line=cohort median 		6.3 6.3 62.0%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.8
bar=donor   line=cohort median 		3.4 3.4 18.2%
12 GNLY protein_coding 4.8
bar=donor   line=cohort median 		4.9 4.9 42.1%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 4.9
bar=donor   line=cohort median 		6.6 6.6 11.3%
14 HBA1 protein_coding -1.8
bar=donor   line=cohort median 		2.6 2.6 0.3%
15 HBA2 protein_coding 2.6
bar=donor   line=cohort median 		5.6 5.6 9.2%
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