GSM5528561

Dataset: gse182409 • Sample: T065 • Status: Pregnancy-stage cohort
◂ Prev All Donors Next ▸

Quality Control Metrics

56,578,379 Total counts Group median: 70,855,220 • 17.5%ile (↓ Low)
28,773 Detected genes Group median: 31,576 • 24.3%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 92.8%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

36.8Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.41
bar=donor   line=cohort median 		9.31 58.3%
CETP Lipid Metabolism 1.16
bar=donor   line=cohort median 		1.18 47.2%
SIRT6 Sirtuin Family 2.03
bar=donor   line=cohort median 		2.22 25.9%
SIRT1 Sirtuin Family 5.72
bar=donor   line=cohort median 		5.50 88.6%
SIRT3 Sirtuin Family 2.11
bar=donor   line=cohort median 		2.33 19.0%
IGF1R Insulin/IGF-1 Signaling 6.59
bar=donor   line=cohort median 		7.09 10.0%
KLOTHO Anti-aging 0.99
bar=donor   line=cohort median 		0.66 70.7%
IRS2 Insulin/IGF-1 Signaling 4.66
bar=donor   line=cohort median 		5.59 3.1%
TP53 Tumor Suppression 2.42
bar=donor   line=cohort median 		2.72 34.8%
SHC1 Signal Transduction 3.65
bar=donor   line=cohort median 		3.95 10.7%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.2 973,010
2 ENSG00000265150 ENSG00000265150 13.9 805,575
3 ENSG00000258486 ENSG00000258486 13.7 690,574
4 BNIP3L ENSG00000104765 protein_coding 13.3 509,535
5 MALAT1 ENSG00000251562 lncRNA 13.2 478,934
6 ALAS2 ENSG00000158578 protein_coding 13.1 469,046
7 EPB41 ENSG00000159023 protein_coding 12.9 399,456
8 B2M ENSG00000166710 protein_coding 12.8 376,076
9 AL355075.4 ENSG00000259001 lncRNA 12.7 356,349
10 SLC25A37 ENSG00000147454 protein_coding 12.5 304,076

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.1
bar=donor   line=cohort median 		11.8 11.8 8.6%
2 S100A9 protein_coding 12.4
bar=donor   line=cohort median 		13.1 13.1 6.5%
3 IL1B protein_coding 5.2
bar=donor   line=cohort median 		6.9 6.9 0.3%
4 CXCL8 protein_coding 6.3
bar=donor   line=cohort median 		7.6 7.6 13.4%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.3
bar=donor   line=cohort median 		4.0 4.0 59.9%
6 FCGR3B protein_coding 11.3
bar=donor   line=cohort median 		11.3 11.3 44.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.5
bar=donor   line=cohort median 		10.9 10.9 22.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.4
bar=donor   line=cohort median 		5.3 5.3 57.2%
9 CD3E protein_coding 3.4
bar=donor   line=cohort median 		2.6 2.6 87.3%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.9
bar=donor   line=cohort median 		6.3 6.3 90.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.6
bar=donor   line=cohort median 		3.4 3.4 57.2%
12 GNLY protein_coding 5.2
bar=donor   line=cohort median 		4.9 4.9 69.5%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 6.5
bar=donor   line=cohort median 		6.6 6.6 46.2%
14 HBA1 protein_coding 5.0
bar=donor   line=cohort median 		2.6 2.6 76.4%
15 HBA2 protein_coding 7.9
bar=donor   line=cohort median 		5.6 5.6 74.3%
◂ Previous Donor Back to Donor List Next Donor ▸