GSM5528563

Dataset: gse182409 • Sample: T067 • Status: Pregnancy-stage cohort
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Quality Control Metrics

75,401,418 Total counts Group median: 70,855,220 • 59.2%ile (≈ Median)
29,496 Detected genes Group median: 31,576 • 30.5%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 90.1%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

62.0Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 10.12
bar=donor   line=cohort median 		9.31 94.8%
CETP Lipid Metabolism 1.94
bar=donor   line=cohort median 		1.18 88.6%
SIRT6 Sirtuin Family 1.84
bar=donor   line=cohort median 		2.22 11.4%
SIRT1 Sirtuin Family 5.49
bar=donor   line=cohort median 		5.50 45.2%
SIRT3 Sirtuin Family 2.44
bar=donor   line=cohort median 		2.33 68.6%
IGF1R Insulin/IGF-1 Signaling 7.39
bar=donor   line=cohort median 		7.09 81.0%
KLOTHO Anti-aging 0.93
bar=donor   line=cohort median 		0.66 67.9%
IRS2 Insulin/IGF-1 Signaling 5.39
bar=donor   line=cohort median 		5.59 32.1%
TP53 Tumor Suppression 2.95
bar=donor   line=cohort median 		2.72 65.2%
SHC1 Signal Transduction 4.04
bar=donor   line=cohort median 		3.95 65.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.3 1,530,580
2 ENSG00000258486 ENSG00000258486 13.7 989,968
3 ENSG00000265150 ENSG00000265150 13.7 979,597
4 MALAT1 ENSG00000251562 lncRNA 13.5 875,701
5 ALAS2 ENSG00000158578 protein_coding 13.1 680,530
6 B2M ENSG00000166710 protein_coding 13.1 673,876
7 S100A9 ENSG00000163220 protein_coding 13.1 660,155
8 AL355075.4 ENSG00000259001 lncRNA 12.9 566,071
9 NAMPT ENSG00000105835 protein_coding 12.8 521,720
10 SLC25A37 ENSG00000147454 protein_coding 12.5 429,400

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.1
bar=donor   line=cohort median 		11.8 11.8 75.0%
2 S100A9 protein_coding 13.1
bar=donor   line=cohort median 		13.1 13.1 49.0%
3 IL1B protein_coding 5.5
bar=donor   line=cohort median 		6.9 6.9 3.1%
4 CXCL8 protein_coding 8.5
bar=donor   line=cohort median 		7.6 7.6 83.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 6.3
bar=donor   line=cohort median 		4.0 4.0 95.5%
6 FCGR3B protein_coding 11.0
bar=donor   line=cohort median 		11.3 11.3 23.6%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.0
bar=donor   line=cohort median 		10.9 10.9 62.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.1
bar=donor   line=cohort median 		5.3 5.3 23.6%
9 CD3E protein_coding 2.6
bar=donor   line=cohort median 		2.6 2.6 48.3%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.7
bar=donor   line=cohort median 		6.3 6.3 75.7%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.0
bar=donor   line=cohort median 		3.4 3.4 75.0%
12 GNLY protein_coding 4.7
bar=donor   line=cohort median 		4.9 4.9 37.3%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 4.8
bar=donor   line=cohort median 		6.6 6.6 9.2%
14 HBA1 protein_coding 2.4
bar=donor   line=cohort median 		2.6 2.6 46.9%
15 HBA2 protein_coding 5.4
bar=donor   line=cohort median 		5.6 5.6 46.2%
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