GSM5528564

Dataset: gse182409 • Sample: T068 • Status: Pregnancy-stage cohort
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Quality Control Metrics

49,289,788 Total counts Group median: 70,855,220 • 6.5%ile (↓ Low)
26,861 Detected genes Group median: 31,576 • 5.1%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 39.4%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

48.3Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.69
bar=donor   line=cohort median 		9.31 79.0%
CETP Lipid Metabolism 0.59
bar=donor   line=cohort median 		1.18 12.1%
SIRT6 Sirtuin Family 2.14
bar=donor   line=cohort median 		2.22 42.4%
SIRT1 Sirtuin Family 5.48
bar=donor   line=cohort median 		5.50 39.0%
SIRT3 Sirtuin Family 2.00
bar=donor   line=cohort median 		2.33 10.0%
IGF1R Insulin/IGF-1 Signaling 7.37
bar=donor   line=cohort median 		7.09 79.7%
KLOTHO Anti-aging 0.43
bar=donor   line=cohort median 		0.66 28.6%
IRS2 Insulin/IGF-1 Signaling 6.05
bar=donor   line=cohort median 		5.59 87.2%
TP53 Tumor Suppression 2.54
bar=donor   line=cohort median 		2.72 40.3%
SHC1 Signal Transduction 4.04
bar=donor   line=cohort median 		3.95 64.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.2 874,286
2 ENSG00000258486 ENSG00000258486 14.2 835,236
3 7SK ENSG00000202198 misc_RNA 14.0 724,852
4 ALAS2 ENSG00000158578 protein_coding 13.8 646,617
5 MALAT1 ENSG00000251562 lncRNA 13.4 497,152
6 B2M ENSG00000166710 protein_coding 12.7 313,778
7 EPB41 ENSG00000159023 protein_coding 12.7 310,501
8 S100A9 ENSG00000163220 protein_coding 12.7 307,571
9 AL355075.4 ENSG00000259001 lncRNA 12.7 299,443
10 SLC25A37 ENSG00000147454 protein_coding 12.5 264,935

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.6
bar=donor   line=cohort median 		11.8 11.8 38.0%
2 S100A9 protein_coding 12.7
bar=donor   line=cohort median 		13.1 13.1 22.9%
3 IL1B protein_coding 6.5
bar=donor   line=cohort median 		6.9 6.9 27.7%
4 CXCL8 protein_coding 7.2
bar=donor   line=cohort median 		7.6 7.6 38.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.9
bar=donor   line=cohort median 		4.0 4.0 70.9%
6 FCGR3B protein_coding 11.3
bar=donor   line=cohort median 		11.3 11.3 52.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.6
bar=donor   line=cohort median 		10.9 10.9 25.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.2
bar=donor   line=cohort median 		5.3 5.3 37.3%
9 CD3E protein_coding 2.8
bar=donor   line=cohort median 		2.6 2.6 58.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.9
bar=donor   line=cohort median 		6.3 6.3 84.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.8
bar=donor   line=cohort median 		3.4 3.4 69.5%
12 GNLY protein_coding 4.5
bar=donor   line=cohort median 		4.9 4.9 25.7%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 6.7
bar=donor   line=cohort median 		6.6 6.6 51.7%
14 HBA1 protein_coding 4.6
bar=donor   line=cohort median 		2.6 2.6 71.6%
15 HBA2 protein_coding 7.5
bar=donor   line=cohort median 		5.6 5.6 68.8%
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