GSM5528566

Dataset: gse182409 • Sample: T070 • Status: Pregnancy-stage cohort
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Quality Control Metrics

83,125,445 Total counts Group median: 70,855,220 • 78.4%ile (↑ High)
28,738 Detected genes Group median: 31,576 • 23.6%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 5.8%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

57.2Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.70
bar=donor   line=cohort median 		9.31 79.7%
CETP Lipid Metabolism -0.22
bar=donor   line=cohort median 		1.18 1.0%
SIRT6 Sirtuin Family 2.27
bar=donor   line=cohort median 		2.22 59.0%
SIRT1 Sirtuin Family 5.42
bar=donor   line=cohort median 		5.50 30.0%
SIRT3 Sirtuin Family 2.79
bar=donor   line=cohort median 		2.33 94.1%
IGF1R Insulin/IGF-1 Signaling 7.26
bar=donor   line=cohort median 		7.09 72.1%
KLOTHO Anti-aging 0.60
bar=donor   line=cohort median 		0.66 44.5%
IRS2 Insulin/IGF-1 Signaling 5.66
bar=donor   line=cohort median 		5.59 55.5%
TP53 Tumor Suppression 3.13
bar=donor   line=cohort median 		2.72 76.2%
SHC1 Signal Transduction 4.01
bar=donor   line=cohort median 		3.95 60.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.6 3,624,675
2 ENSG00000258486 ENSG00000258486 15.5 3,264,928
3 7SK ENSG00000202198 misc_RNA 14.8 1,973,132
4 AL355075.4 ENSG00000259001 lncRNA 13.8 1,049,957
5 ALAS2 ENSG00000158578 protein_coding 13.7 919,828
6 B2M ENSG00000166710 protein_coding 13.4 754,472
7 S100A9 ENSG00000163220 protein_coding 13.3 694,548
8 MALAT1 ENSG00000251562 lncRNA 13.2 677,821
9 SLC25A37 ENSG00000147454 protein_coding 13.1 615,245
10 BNIP3L ENSG00000104765 protein_coding 12.6 450,092

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.0
bar=donor   line=cohort median 		11.8 11.8 66.8%
2 S100A9 protein_coding 13.3
bar=donor   line=cohort median 		13.1 13.1 68.2%
3 IL1B protein_coding 6.9
bar=donor   line=cohort median 		6.9 6.9 55.8%
4 CXCL8 protein_coding 7.3
bar=donor   line=cohort median 		7.6 7.6 43.5%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.2
bar=donor   line=cohort median 		4.0 4.0 81.8%
6 FCGR3B protein_coding 11.6
bar=donor   line=cohort median 		11.3 11.3 68.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.8
bar=donor   line=cohort median 		10.9 10.9 41.4%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.1
bar=donor   line=cohort median 		5.3 5.3 33.9%
9 CD3E protein_coding 1.5
bar=donor   line=cohort median 		2.6 2.6 6.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.6
bar=donor   line=cohort median 		6.3 6.3 71.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.2
bar=donor   line=cohort median 		3.4 3.4 38.0%
12 GNLY protein_coding 4.0
bar=donor   line=cohort median 		4.9 4.9 9.9%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 8.0
bar=donor   line=cohort median 		6.6 6.6 68.2%
14 HBA1 protein_coding 1.8
bar=donor   line=cohort median 		2.6 2.6 40.8%
15 HBA2 protein_coding 4.7
bar=donor   line=cohort median 		5.6 5.6 37.3%
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