GSM5528567

Dataset: gse182409 • Sample: T071 • Status: Pregnancy-stage cohort
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Quality Control Metrics

86,706,260 Total counts Group median: 70,855,220 • 85.3%ile (↑ High)
31,890 Detected genes Group median: 31,576 • 57.2%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 55.1%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

44.6Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.85
bar=donor   line=cohort median 		9.31 86.6%
CETP Lipid Metabolism 0.95
bar=donor   line=cohort median 		1.18 34.1%
SIRT6 Sirtuin Family 2.13
bar=donor   line=cohort median 		2.22 41.0%
SIRT1 Sirtuin Family 5.43
bar=donor   line=cohort median 		5.50 31.4%
SIRT3 Sirtuin Family 1.98
bar=donor   line=cohort median 		2.33 6.6%
IGF1R Insulin/IGF-1 Signaling 7.22
bar=donor   line=cohort median 		7.09 67.9%
KLOTHO Anti-aging 0.64
bar=donor   line=cohort median 		0.66 47.2%
IRS2 Insulin/IGF-1 Signaling 5.54
bar=donor   line=cohort median 		5.59 41.7%
TP53 Tumor Suppression 2.39
bar=donor   line=cohort median 		2.72 30.7%
SHC1 Signal Transduction 4.00
bar=donor   line=cohort median 		3.95 58.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.6 3,233,223
2 ENSG00000258486 ENSG00000258486 15.5 3,103,885
3 7SK ENSG00000202198 misc_RNA 14.6 1,647,188
4 S100A9 ENSG00000163220 protein_coding 13.7 880,877
5 AL355075.4 ENSG00000259001 lncRNA 13.6 832,586
6 B2M ENSG00000166710 protein_coding 13.4 715,196
7 ALAS2 ENSG00000158578 protein_coding 13.4 704,742
8 BNIP3L ENSG00000104765 protein_coding 13.3 661,509
9 SLC25A37 ENSG00000147454 protein_coding 13.2 611,033
10 NAMPT ENSG00000105835 protein_coding 12.9 524,354

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.3
bar=donor   line=cohort median 		11.8 11.8 88.0%
2 S100A9 protein_coding 13.7
bar=donor   line=cohort median 		13.1 13.1 92.1%
3 IL1B protein_coding 7.1
bar=donor   line=cohort median 		6.9 6.9 72.9%
4 CXCL8 protein_coding 8.2
bar=donor   line=cohort median 		7.6 7.6 75.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.2
bar=donor   line=cohort median 		4.0 4.0 55.8%
6 FCGR3B protein_coding 11.0
bar=donor   line=cohort median 		11.3 11.3 24.3%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.5
bar=donor   line=cohort median 		10.9 10.9 20.2%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.5
bar=donor   line=cohort median 		5.3 5.3 75.0%
9 CD3E protein_coding 3.0
bar=donor   line=cohort median 		2.6 2.6 69.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.3
bar=donor   line=cohort median 		6.3 6.3 53.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.7
bar=donor   line=cohort median 		3.4 3.4 62.7%
12 GNLY protein_coding 4.9
bar=donor   line=cohort median 		4.9 4.9 55.1%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 9.7
bar=donor   line=cohort median 		6.6 6.6 86.6%
14 HBA1 protein_coding 5.0
bar=donor   line=cohort median 		2.6 2.6 75.7%
15 HBA2 protein_coding 8.2
bar=donor   line=cohort median 		5.6 5.6 78.4%
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