GSM5528568

Dataset: gse182409 • Sample: T072 • Status: Pregnancy-stage cohort
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Quality Control Metrics

95,681,183 Total counts Group median: 70,855,220 • 94.2%ile (↑ High)
32,589 Detected genes Group median: 31,576 • 73.6%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 27.1%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

48.1Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 10.12
bar=donor   line=cohort median 		9.31 94.1%
CETP Lipid Metabolism 0.79
bar=donor   line=cohort median 		1.18 20.3%
SIRT6 Sirtuin Family 2.38
bar=donor   line=cohort median 		2.22 73.5%
SIRT1 Sirtuin Family 5.40
bar=donor   line=cohort median 		5.50 23.8%
SIRT3 Sirtuin Family 1.76
bar=donor   line=cohort median 		2.33 1.0%
IGF1R Insulin/IGF-1 Signaling 7.24
bar=donor   line=cohort median 		7.09 70.0%
KLOTHO Anti-aging 0.59
bar=donor   line=cohort median 		0.66 43.1%
IRS2 Insulin/IGF-1 Signaling 5.69
bar=donor   line=cohort median 		5.59 61.0%
TP53 Tumor Suppression 2.46
bar=donor   line=cohort median 		2.72 36.9%
SHC1 Signal Transduction 4.00
bar=donor   line=cohort median 		3.95 57.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.5 3,998,529
2 ENSG00000258486 ENSG00000258486 15.3 3,506,397
3 7SK ENSG00000202198 misc_RNA 14.3 1,710,625
4 B2M ENSG00000166710 protein_coding 13.6 1,040,724
5 MALAT1 ENSG00000251562 lncRNA 13.4 916,379
6 AL355075.4 ENSG00000259001 lncRNA 13.2 790,875
7 S100A9 ENSG00000163220 protein_coding 13.1 778,927
8 BNIP3L ENSG00000104765 protein_coding 13.0 708,785
9 NAMPT ENSG00000105835 protein_coding 13.0 688,918
10 SORL1 ENSG00000137642 protein_coding 12.5 485,405

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.9
bar=donor   line=cohort median 		11.8 11.8 54.5%
2 S100A9 protein_coding 13.1
bar=donor   line=cohort median 		13.1 13.1 51.7%
3 IL1B protein_coding 6.3
bar=donor   line=cohort median 		6.9 6.9 19.5%
4 CXCL8 protein_coding 8.2
bar=donor   line=cohort median 		7.6 7.6 71.6%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 2.3
bar=donor   line=cohort median 		4.0 4.0 7.9%
6 FCGR3B protein_coding 12.3
bar=donor   line=cohort median 		11.3 11.3 96.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.8
bar=donor   line=cohort median 		10.9 10.9 38.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.2
bar=donor   line=cohort median 		5.3 5.3 44.9%
9 CD3E protein_coding 1.5
bar=donor   line=cohort median 		2.6 2.6 5.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.7
bar=donor   line=cohort median 		6.3 6.3 78.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 1.7
bar=donor   line=cohort median 		3.4 3.4 0.3%
12 GNLY protein_coding 3.2
bar=donor   line=cohort median 		4.9 4.9 1.0%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 4.2
bar=donor   line=cohort median 		6.6 6.6 2.4%
14 HBA1 protein_coding -0.4
bar=donor   line=cohort median 		2.6 2.6 13.4%
15 HBA2 protein_coding 2.5
bar=donor   line=cohort median 		5.6 5.6 7.9%
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