GSM5528569

Dataset: gse182409 • Sample: T073 • Status: Pregnancy-stage cohort
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Quality Control Metrics

77,453,320 Total counts Group median: 70,855,220 • 64.0%ile (≈ Median)
32,067 Detected genes Group median: 31,576 • 61.3%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 48.3%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

32.1Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.22
bar=donor   line=cohort median 		9.31 43.8%
CETP Lipid Metabolism 0.75
bar=donor   line=cohort median 		1.18 19.0%
SIRT6 Sirtuin Family 2.03
bar=donor   line=cohort median 		2.22 25.2%
SIRT1 Sirtuin Family 5.85
bar=donor   line=cohort median 		5.50 96.2%
SIRT3 Sirtuin Family 1.98
bar=donor   line=cohort median 		2.33 7.2%
IGF1R Insulin/IGF-1 Signaling 6.83
bar=donor   line=cohort median 		7.09 24.5%
KLOTHO Anti-aging 0.63
bar=donor   line=cohort median 		0.66 46.6%
IRS2 Insulin/IGF-1 Signaling 5.49
bar=donor   line=cohort median 		5.59 39.7%
TP53 Tumor Suppression 1.87
bar=donor   line=cohort median 		2.72 5.9%
SHC1 Signal Transduction 3.69
bar=donor   line=cohort median 		3.95 12.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.0 2,090,188
2 ENSG00000258486 ENSG00000258486 14.9 1,957,139
3 7SK ENSG00000202198 misc_RNA 14.6 1,579,382
4 MALAT1 ENSG00000251562 lncRNA 13.8 957,783
5 AL355075.4 ENSG00000259001 lncRNA 13.6 802,715
6 S100A9 ENSG00000163220 protein_coding 13.5 778,587
7 B2M ENSG00000166710 protein_coding 13.4 712,049
8 ALAS2 ENSG00000158578 protein_coding 13.1 597,070
9 NAMPT ENSG00000105835 protein_coding 12.8 470,176
10 SLC25A37 ENSG00000147454 protein_coding 12.8 458,126

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.2
bar=donor   line=cohort median 		11.8 11.8 86.0%
2 S100A9 protein_coding 13.5
bar=donor   line=cohort median 		13.1 13.1 86.0%
3 IL1B protein_coding 7.3
bar=donor   line=cohort median 		6.9 6.9 83.2%
4 CXCL8 protein_coding 7.3
bar=donor   line=cohort median 		7.6 7.6 42.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.0
bar=donor   line=cohort median 		4.0 4.0 47.6%
6 FCGR3B protein_coding 11.7
bar=donor   line=cohort median 		11.3 11.3 78.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.9
bar=donor   line=cohort median 		10.9 10.9 47.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 4.9
bar=donor   line=cohort median 		5.3 5.3 14.0%
9 CD3E protein_coding 1.2
bar=donor   line=cohort median 		2.6 2.6 0.3%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.8
bar=donor   line=cohort median 		6.3 6.3 20.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.5
bar=donor   line=cohort median 		3.4 3.4 10.6%
12 GNLY protein_coding 4.5
bar=donor   line=cohort median 		4.9 4.9 26.4%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 4.7
bar=donor   line=cohort median 		6.6 6.6 8.6%
14 HBA1 protein_coding 0.8
bar=donor   line=cohort median 		2.6 2.6 29.8%
15 HBA2 protein_coding 3.8
bar=donor   line=cohort median 		5.6 5.6 29.8%
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