GSM5528570

Dataset: gse182409 • Sample: T074 • Status: Pregnancy-stage cohort
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Quality Control Metrics

120,016,950 Total counts Group median: 70,855,220 • 99.0%ile (↑ High)
32,651 Detected genes Group median: 31,576 • 75.0%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 29.8%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

49.9Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.21
bar=donor   line=cohort median 		9.31 42.4%
CETP Lipid Metabolism 1.25
bar=donor   line=cohort median 		1.18 54.1%
SIRT6 Sirtuin Family 2.35
bar=donor   line=cohort median 		2.22 68.6%
SIRT1 Sirtuin Family 5.66
bar=donor   line=cohort median 		5.50 81.0%
SIRT3 Sirtuin Family 2.23
bar=donor   line=cohort median 		2.33 34.1%
IGF1R Insulin/IGF-1 Signaling 7.43
bar=donor   line=cohort median 		7.09 85.2%
KLOTHO Anti-aging 0.41
bar=donor   line=cohort median 		0.66 26.6%
IRS2 Insulin/IGF-1 Signaling 5.38
bar=donor   line=cohort median 		5.59 31.4%
TP53 Tumor Suppression 1.88
bar=donor   line=cohort median 		2.72 6.6%
SHC1 Signal Transduction 4.07
bar=donor   line=cohort median 		3.95 68.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 16.0 5,963,853
2 ENSG00000258486 ENSG00000258486 15.5 4,459,407
3 7SK ENSG00000202198 misc_RNA 14.6 2,326,267
4 ALAS2 ENSG00000158578 protein_coding 14.2 1,787,524
5 AL355075.4 ENSG00000259001 lncRNA 13.5 1,098,292
6 B2M ENSG00000166710 protein_coding 13.4 993,549
7 SLC25A37 ENSG00000147454 protein_coding 13.3 968,078
8 S100A9 ENSG00000163220 protein_coding 13.2 876,754
9 BNIP3L ENSG00000104765 protein_coding 13.1 813,400
10 EPB41 ENSG00000159023 protein_coding 13.1 801,743

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.8
bar=donor   line=cohort median 		11.8 11.8 48.3%
2 S100A9 protein_coding 13.2
bar=donor   line=cohort median 		13.1 13.1 57.2%
3 IL1B protein_coding 7.3
bar=donor   line=cohort median 		6.9 6.9 79.1%
4 CXCL8 protein_coding 8.9
bar=donor   line=cohort median 		7.6 7.6 92.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.8
bar=donor   line=cohort median 		4.0 4.0 44.9%
6 FCGR3B protein_coding 11.4
bar=donor   line=cohort median 		11.3 11.3 59.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.0
bar=donor   line=cohort median 		10.9 10.9 62.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.5
bar=donor   line=cohort median 		5.3 5.3 69.5%
9 CD3E protein_coding 2.4
bar=donor   line=cohort median 		2.6 2.6 38.0%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.5
bar=donor   line=cohort median 		6.3 6.3 5.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.7
bar=donor   line=cohort median 		3.4 3.4 17.5%
12 GNLY protein_coding 4.8
bar=donor   line=cohort median 		4.9 4.9 40.8%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 8.9
bar=donor   line=cohort median 		6.6 6.6 77.1%
14 HBA1 protein_coding 4.8
bar=donor   line=cohort median 		2.6 2.6 73.6%
15 HBA2 protein_coding 7.8
bar=donor   line=cohort median 		5.6 5.6 71.6%
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