GSM5528572

Dataset: gse182409 • Sample: T076 • Status: Pregnancy-stage cohort
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Quality Control Metrics

85,733,842 Total counts Group median: 70,855,220 • 84.6%ile (↑ High)
29,255 Detected genes Group median: 31,576 • 27.7%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 3.8%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

38.8Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.70
bar=donor   line=cohort median 		9.31 80.3%
CETP Lipid Metabolism 0.87
bar=donor   line=cohort median 		1.18 27.9%
SIRT6 Sirtuin Family 2.09
bar=donor   line=cohort median 		2.22 34.8%
SIRT1 Sirtuin Family 5.61
bar=donor   line=cohort median 		5.50 72.1%
SIRT3 Sirtuin Family 2.28
bar=donor   line=cohort median 		2.33 45.9%
IGF1R Insulin/IGF-1 Signaling 6.64
bar=donor   line=cohort median 		7.09 12.1%
KLOTHO Anti-aging 0.45
bar=donor   line=cohort median 		0.66 30.7%
IRS2 Insulin/IGF-1 Signaling 5.07
bar=donor   line=cohort median 		5.59 14.1%
TP53 Tumor Suppression 2.15
bar=donor   line=cohort median 		2.72 16.9%
SHC1 Signal Transduction 3.97
bar=donor   line=cohort median 		3.95 52.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.1 2,648,051
2 ENSG00000258486 ENSG00000258486 15.0 2,495,010
3 7SK ENSG00000202198 misc_RNA 14.4 1,612,408
4 ALAS2 ENSG00000158578 protein_coding 14.1 1,308,571
5 B2M ENSG00000166710 protein_coding 13.8 1,111,211
6 AL355075.4 ENSG00000259001 lncRNA 13.5 877,565
7 MALAT1 ENSG00000251562 lncRNA 13.5 857,402
8 S100A9 ENSG00000163220 protein_coding 13.3 753,501
9 NAMPT ENSG00000105835 protein_coding 12.6 477,571
10 SLC25A37 ENSG00000147454 protein_coding 12.5 439,319

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.9
bar=donor   line=cohort median 		11.8 11.8 59.2%
2 S100A9 protein_coding 13.3
bar=donor   line=cohort median 		13.1 13.1 70.9%
3 IL1B protein_coding 6.6
bar=donor   line=cohort median 		6.9 6.9 35.3%
4 CXCL8 protein_coding 9.0
bar=donor   line=cohort median 		7.6 7.6 94.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.8
bar=donor   line=cohort median 		4.0 4.0 69.5%
6 FCGR3B protein_coding 11.8
bar=donor   line=cohort median 		11.3 11.3 85.3%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.6
bar=donor   line=cohort median 		10.9 10.9 94.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.2
bar=donor   line=cohort median 		5.3 5.3 45.5%
9 CD3E protein_coding 2.1
bar=donor   line=cohort median 		2.6 2.6 22.9%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.2
bar=donor   line=cohort median 		6.3 6.3 43.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.6
bar=donor   line=cohort median 		3.4 3.4 60.6%
12 GNLY protein_coding 5.4
bar=donor   line=cohort median 		4.9 4.9 82.5%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.0
bar=donor   line=cohort median 		6.6 6.6 12.7%
14 HBA1 protein_coding -0.6
bar=donor   line=cohort median 		2.6 2.6 8.6%
15 HBA2 protein_coding 2.2
bar=donor   line=cohort median 		5.6 5.6 4.5%
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