GSM5528573

Dataset: gse182409 • Sample: T077 • Status: Pregnancy-stage cohort
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Quality Control Metrics

62,005,750 Total counts Group median: 70,855,220 • 25.0%ile (≈ Median)
31,189 Detected genes Group median: 31,576 • 44.2%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 40.1%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

36.6Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.48
bar=donor   line=cohort median 		9.31 64.5%
CETP Lipid Metabolism 1.69
bar=donor   line=cohort median 		1.18 80.3%
SIRT6 Sirtuin Family 1.84
bar=donor   line=cohort median 		2.22 10.0%
SIRT1 Sirtuin Family 5.42
bar=donor   line=cohort median 		5.50 28.6%
SIRT3 Sirtuin Family 2.77
bar=donor   line=cohort median 		2.33 92.8%
IGF1R Insulin/IGF-1 Signaling 6.41
bar=donor   line=cohort median 		7.09 5.2%
KLOTHO Anti-aging 0.40
bar=donor   line=cohort median 		0.66 25.9%
IRS2 Insulin/IGF-1 Signaling 5.43
bar=donor   line=cohort median 		5.59 34.1%
TP53 Tumor Suppression 2.25
bar=donor   line=cohort median 		2.72 23.8%
SHC1 Signal Transduction 3.42
bar=donor   line=cohort median 		3.95 1.0%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.2 2,248,443
2 ENSG00000258486 ENSG00000258486 15.0 1,966,311
3 7SK ENSG00000202198 misc_RNA 14.5 1,374,910
4 ALAS2 ENSG00000158578 protein_coding 13.7 793,668
5 MALAT1 ENSG00000251562 lncRNA 13.4 666,469
6 B2M ENSG00000166710 protein_coding 13.3 605,328
7 AL355075.4 ENSG00000259001 lncRNA 13.3 595,235
8 S100A9 ENSG00000163220 protein_coding 13.1 527,303
9 TMSB4X ENSG00000205542 protein_coding 12.4 327,118
10 SLC25A37 ENSG00000147454 protein_coding 12.3 309,871

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.9
bar=donor   line=cohort median 		11.8 11.8 57.2%
2 S100A9 protein_coding 13.1
bar=donor   line=cohort median 		13.1 13.1 48.3%
3 IL1B protein_coding 6.2
bar=donor   line=cohort median 		6.9 6.9 14.0%
4 CXCL8 protein_coding 5.2
bar=donor   line=cohort median 		7.6 7.6 2.4%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.6
bar=donor   line=cohort median 		4.0 4.0 90.1%
6 FCGR3B protein_coding 10.8
bar=donor   line=cohort median 		11.3 11.3 14.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.6
bar=donor   line=cohort median 		10.9 10.9 95.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.4
bar=donor   line=cohort median 		5.3 5.3 58.6%
9 CD3E protein_coding 2.5
bar=donor   line=cohort median 		2.6 2.6 44.9%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.7
bar=donor   line=cohort median 		6.3 6.3 15.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.3
bar=donor   line=cohort median 		3.4 3.4 44.2%
12 GNLY protein_coding 4.2
bar=donor   line=cohort median 		4.9 4.9 12.7%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 7.4
bar=donor   line=cohort median 		6.6 6.6 59.2%
14 HBA1 protein_coding 1.5
bar=donor   line=cohort median 		2.6 2.6 36.6%
15 HBA2 protein_coding 3.9
bar=donor   line=cohort median 		5.6 5.6 31.8%
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