GSM5528574

Dataset: gse182409 • Sample: T078 • Status: Pregnancy-stage cohort
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Quality Control Metrics

124,984,591 Total counts Group median: 70,855,220 • 99.7%ile (↑ High)
34,578 Detected genes Group median: 31,576 • 98.3%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 35.3%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

29.2Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.22
bar=donor   line=cohort median 		9.31 43.1%
CETP Lipid Metabolism 0.91
bar=donor   line=cohort median 		1.18 30.7%
SIRT6 Sirtuin Family 1.78
bar=donor   line=cohort median 		2.22 5.9%
SIRT1 Sirtuin Family 5.32
bar=donor   line=cohort median 		5.50 12.1%
SIRT3 Sirtuin Family 2.16
bar=donor   line=cohort median 		2.33 24.5%
IGF1R Insulin/IGF-1 Signaling 7.10
bar=donor   line=cohort median 		7.09 52.1%
KLOTHO Anti-aging 0.78
bar=donor   line=cohort median 		0.66 59.0%
IRS2 Insulin/IGF-1 Signaling 5.09
bar=donor   line=cohort median 		5.59 15.5%
TP53 Tumor Suppression 2.65
bar=donor   line=cohort median 		2.72 45.9%
SHC1 Signal Transduction 3.52
bar=donor   line=cohort median 		3.95 3.1%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000258486 ENSG00000258486 15.8 6,327,934
2 ENSG00000265150 ENSG00000265150 15.7 6,160,840
3 7SK ENSG00000202198 misc_RNA 14.7 3,056,486
4 AL355075.4 ENSG00000259001 lncRNA 13.5 1,322,748
5 S100A9 ENSG00000163220 protein_coding 13.5 1,290,359
6 MALAT1 ENSG00000251562 lncRNA 13.3 1,118,909
7 B2M ENSG00000166710 protein_coding 13.2 1,028,196
8 ALAS2 ENSG00000158578 protein_coding 13.0 921,039
9 NAMPT ENSG00000105835 protein_coding 12.5 662,190
10 EEF1A1 ENSG00000156508 protein_coding 12.4 610,277

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.1
bar=donor   line=cohort median 		11.8 11.8 75.7%
2 S100A9 protein_coding 13.5
bar=donor   line=cohort median 		13.1 13.1 82.5%
3 IL1B protein_coding 6.3
bar=donor   line=cohort median 		6.9 6.9 21.6%
4 CXCL8 protein_coding 9.2
bar=donor   line=cohort median 		7.6 7.6 94.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.1
bar=donor   line=cohort median 		4.0 4.0 78.4%
6 FCGR3B protein_coding 11.2
bar=donor   line=cohort median 		11.3 11.3 37.3%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.6
bar=donor   line=cohort median 		10.9 10.9 92.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.1
bar=donor   line=cohort median 		5.3 5.3 26.4%
9 CD3E protein_coding 1.5
bar=donor   line=cohort median 		2.6 2.6 7.9%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.6
bar=donor   line=cohort median 		6.3 6.3 7.2%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.2
bar=donor   line=cohort median 		3.4 3.4 38.7%
12 GNLY protein_coding 4.4
bar=donor   line=cohort median 		4.9 4.9 25.0%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.5
bar=donor   line=cohort median 		6.6 6.6 25.7%
14 HBA1 protein_coding 2.2
bar=donor   line=cohort median 		2.6 2.6 46.2%
15 HBA2 protein_coding 5.5
bar=donor   line=cohort median 		5.6 5.6 47.6%
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