GSM5528575

Dataset: gse182409 • Sample: T079 • Status: Pregnancy-stage cohort
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Quality Control Metrics

68,959,490 Total counts Group median: 70,855,220 • 44.9%ile (≈ Median)
32,095 Detected genes Group median: 31,576 • 62.7%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 72.9%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

60.1Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.11
bar=donor   line=cohort median 		9.31 34.1%
CETP Lipid Metabolism 1.03
bar=donor   line=cohort median 		1.18 39.0%
SIRT6 Sirtuin Family 2.47
bar=donor   line=cohort median 		2.22 83.1%
SIRT1 Sirtuin Family 5.64
bar=donor   line=cohort median 		5.50 77.6%
SIRT3 Sirtuin Family 2.33
bar=donor   line=cohort median 		2.33 52.1%
IGF1R Insulin/IGF-1 Signaling 7.27
bar=donor   line=cohort median 		7.09 73.5%
KLOTHO Anti-aging 0.56
bar=donor   line=cohort median 		0.66 40.3%
IRS2 Insulin/IGF-1 Signaling 5.96
bar=donor   line=cohort median 		5.59 83.1%
TP53 Tumor Suppression 2.55
bar=donor   line=cohort median 		2.72 42.4%
SHC1 Signal Transduction 4.15
bar=donor   line=cohort median 		3.95 76.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000258486 ENSG00000258486 15.9 3,508,153
2 ENSG00000265150 ENSG00000265150 15.6 3,041,835
3 7SK ENSG00000202198 misc_RNA 15.0 1,991,571
4 AL355075.4 ENSG00000259001 lncRNA 13.6 722,031
5 B2M ENSG00000166710 protein_coding 13.5 709,375
6 S100A9 ENSG00000163220 protein_coding 13.3 601,682
7 BNIP3L ENSG00000104765 protein_coding 13.2 568,827
8 MALAT1 ENSG00000251562 lncRNA 12.9 468,069
9 ALAS2 ENSG00000158578 protein_coding 12.8 427,703
10 NAMPT ENSG00000105835 protein_coding 12.7 386,217

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.1
bar=donor   line=cohort median 		11.8 11.8 74.3%
2 S100A9 protein_coding 13.3
bar=donor   line=cohort median 		13.1 13.1 73.6%
3 IL1B protein_coding 5.9
bar=donor   line=cohort median 		6.9 6.9 7.2%
4 CXCL8 protein_coding 7.4
bar=donor   line=cohort median 		7.6 7.6 44.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.2
bar=donor   line=cohort median 		4.0 4.0 55.1%
6 FCGR3B protein_coding 11.5
bar=donor   line=cohort median 		11.3 11.3 64.7%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.1
bar=donor   line=cohort median 		10.9 10.9 69.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.7
bar=donor   line=cohort median 		5.3 5.3 84.6%
9 CD3E protein_coding 1.9
bar=donor   line=cohort median 		2.6 2.6 14.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 7.0
bar=donor   line=cohort median 		6.3 6.3 92.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.9
bar=donor   line=cohort median 		3.4 3.4 25.7%
12 GNLY protein_coding 4.5
bar=donor   line=cohort median 		4.9 4.9 27.1%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 7.7
bar=donor   line=cohort median 		6.6 6.6 63.4%
14 HBA1 protein_coding 3.7
bar=donor   line=cohort median 		2.6 2.6 62.7%
15 HBA2 protein_coding 6.7
bar=donor   line=cohort median 		5.6 5.6 62.0%
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