GSM5528576

Dataset: gse182409 • Sample: T080 • Status: Pregnancy-stage cohort
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Quality Control Metrics

82,644,683 Total counts Group median: 70,855,220 • 75.0%ile (≈ Median)
29,992 Detected genes Group median: 31,576 • 37.3%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 47.6%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

34.7Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.43
bar=donor   line=cohort median 		9.31 60.3%
CETP Lipid Metabolism 0.61
bar=donor   line=cohort median 		1.18 12.8%
SIRT6 Sirtuin Family 2.23
bar=donor   line=cohort median 		2.22 51.4%
SIRT1 Sirtuin Family 5.52
bar=donor   line=cohort median 		5.50 54.1%
SIRT3 Sirtuin Family 1.91
bar=donor   line=cohort median 		2.33 3.1%
IGF1R Insulin/IGF-1 Signaling 6.86
bar=donor   line=cohort median 		7.09 27.2%
KLOTHO Anti-aging 1.08
bar=donor   line=cohort median 		0.66 76.2%
IRS2 Insulin/IGF-1 Signaling 5.62
bar=donor   line=cohort median 		5.59 53.5%
TP53 Tumor Suppression 1.70
bar=donor   line=cohort median 		2.72 1.0%
SHC1 Signal Transduction 3.62
bar=donor   line=cohort median 		3.95 7.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.4 1,549,213
2 ENSG00000258486 ENSG00000258486 13.8 1,011,912
3 ENSG00000265150 ENSG00000265150 13.7 947,872
4 B2M ENSG00000166710 protein_coding 13.5 866,816
5 ALAS2 ENSG00000158578 protein_coding 13.5 866,161
6 MALAT1 ENSG00000251562 lncRNA 13.3 750,514
7 S100A9 ENSG00000163220 protein_coding 13.3 720,938
8 BNIP3L ENSG00000104765 protein_coding 13.1 640,268
9 AL355075.4 ENSG00000259001 lncRNA 13.1 623,732
10 NAMPT ENSG00000105835 protein_coding 13.0 581,255

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.1
bar=donor   line=cohort median 		11.8 11.8 72.9%
2 S100A9 protein_coding 13.3
bar=donor   line=cohort median 		13.1 13.1 68.8%
3 IL1B protein_coding 6.9
bar=donor   line=cohort median 		6.9 6.9 51.7%
4 CXCL8 protein_coding 8.6
bar=donor   line=cohort median 		7.6 7.6 84.6%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.7
bar=donor   line=cohort median 		4.0 4.0 42.8%
6 FCGR3B protein_coding 11.5
bar=donor   line=cohort median 		11.3 11.3 62.7%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.1
bar=donor   line=cohort median 		10.9 10.9 68.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.2
bar=donor   line=cohort median 		5.3 5.3 44.2%
9 CD3E protein_coding 1.3
bar=donor   line=cohort median 		2.6 2.6 2.4%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.3
bar=donor   line=cohort median 		6.3 6.3 55.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.0
bar=donor   line=cohort median 		3.4 3.4 27.1%
12 GNLY protein_coding 6.0
bar=donor   line=cohort median 		4.9 4.9 94.2%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 9.5
bar=donor   line=cohort median 		6.6 6.6 85.3%
14 HBA1 protein_coding 5.2
bar=donor   line=cohort median 		2.6 2.6 78.4%
15 HBA2 protein_coding 7.8
bar=donor   line=cohort median 		5.6 5.6 72.9%
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