GSM5528578

Dataset: gse182409 • Sample: T082 • Status: Pregnancy-stage cohort
◂ Prev All Donors Next ▸

Quality Control Metrics

51,411,107 Total counts Group median: 70,855,220 • 9.2%ile (↓ Low)
28,637 Detected genes Group median: 31,576 • 20.2%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 22.3%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

51.3Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.88
bar=donor   line=cohort median 		9.31 87.2%
CETP Lipid Metabolism 1.18
bar=donor   line=cohort median 		1.18 51.4%
SIRT6 Sirtuin Family 2.24
bar=donor   line=cohort median 		2.22 53.5%
SIRT1 Sirtuin Family 5.59
bar=donor   line=cohort median 		5.50 66.6%
SIRT3 Sirtuin Family 2.19
bar=donor   line=cohort median 		2.33 27.2%
IGF1R Insulin/IGF-1 Signaling 7.07
bar=donor   line=cohort median 		7.09 48.6%
KLOTHO Anti-aging 0.97
bar=donor   line=cohort median 		0.66 70.0%
IRS2 Insulin/IGF-1 Signaling 5.36
bar=donor   line=cohort median 		5.59 29.3%
TP53 Tumor Suppression 2.10
bar=donor   line=cohort median 		2.72 13.5%
SHC1 Signal Transduction 4.05
bar=donor   line=cohort median 		3.95 65.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.4 908,223
2 ENSG00000265150 ENSG00000265150 14.0 690,058
3 ENSG00000258486 ENSG00000258486 14.0 682,610
4 B2M ENSG00000166710 protein_coding 13.5 485,419
5 MALAT1 ENSG00000251562 lncRNA 13.4 470,074
6 S100A9 ENSG00000163220 protein_coding 13.2 397,443
7 UBB ENSG00000170315 protein_coding 13.0 348,060
8 ALAS2 ENSG00000158578 protein_coding 13.0 335,548
9 BNIP3L ENSG00000104765 protein_coding 12.8 306,833
10 ENSG00000138293 ENSG00000138293 12.7 272,632

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.0
bar=donor   line=cohort median 		11.8 11.8 63.4%
2 S100A9 protein_coding 13.2
bar=donor   line=cohort median 		13.1 13.1 58.6%
3 IL1B protein_coding 8.2
bar=donor   line=cohort median 		6.9 6.9 99.7%
4 CXCL8 protein_coding 6.8
bar=donor   line=cohort median 		7.6 7.6 25.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.9
bar=donor   line=cohort median 		4.0 4.0 46.9%
6 FCGR3B protein_coding 12.0
bar=donor   line=cohort median 		11.3 11.3 93.5%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.0
bar=donor   line=cohort median 		10.9 10.9 58.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 4.6
bar=donor   line=cohort median 		5.3 5.3 3.8%
9 CD3E protein_coding 2.1
bar=donor   line=cohort median 		2.6 2.6 23.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.7
bar=donor   line=cohort median 		6.3 6.3 11.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.0
bar=donor   line=cohort median 		3.4 3.4 27.7%
12 GNLY protein_coding 4.6
bar=donor   line=cohort median 		4.9 4.9 33.2%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 6.7
bar=donor   line=cohort median 		6.6 6.6 50.3%
14 HBA1 protein_coding 5.5
bar=donor   line=cohort median 		2.6 2.6 80.5%
15 HBA2 protein_coding 8.1
bar=donor   line=cohort median 		5.6 5.6 75.7%
◂ Previous Donor Back to Donor List Next Donor ▸