GSM5528579

Dataset: gse182409 • Sample: T083 • Status: Pregnancy-stage cohort
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Quality Control Metrics

83,476,031 Total counts Group median: 70,855,220 • 79.1%ile (↑ High)
31,977 Detected genes Group median: 31,576 • 57.9%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 53.8%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

41.2Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.40
bar=donor   line=cohort median 		9.31 56.2%
CETP Lipid Metabolism 2.54
bar=donor   line=cohort median 		1.18 99.0%
SIRT6 Sirtuin Family 2.05
bar=donor   line=cohort median 		2.22 28.6%
SIRT1 Sirtuin Family 5.26
bar=donor   line=cohort median 		5.50 4.5%
SIRT3 Sirtuin Family 2.09
bar=donor   line=cohort median 		2.33 17.6%
IGF1R Insulin/IGF-1 Signaling 7.20
bar=donor   line=cohort median 		7.09 63.8%
KLOTHO Anti-aging 0.52
bar=donor   line=cohort median 		0.66 33.5%
IRS2 Insulin/IGF-1 Signaling 4.92
bar=donor   line=cohort median 		5.59 9.3%
TP53 Tumor Suppression 2.59
bar=donor   line=cohort median 		2.72 43.8%
SHC1 Signal Transduction 3.99
bar=donor   line=cohort median 		3.95 55.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 16.0 4,342,406
2 ENSG00000258486 ENSG00000258486 15.9 4,069,696
3 7SK ENSG00000202198 misc_RNA 14.6 1,625,972
4 S100A9 ENSG00000163220 protein_coding 13.4 737,965
5 B2M ENSG00000166710 protein_coding 13.4 723,127
6 MALAT1 ENSG00000251562 lncRNA 13.3 651,243
7 AL355075.4 ENSG00000259001 lncRNA 13.2 640,526
8 NAMPT ENSG00000105835 protein_coding 13.2 618,720
9 BNIP3L ENSG00000104765 protein_coding 12.6 399,794
10 SOD2 ENSG00000112096 protein_coding 12.5 386,684

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.0
bar=donor   line=cohort median 		11.8 11.8 68.8%
2 S100A9 protein_coding 13.4
bar=donor   line=cohort median 		13.1 13.1 81.2%
3 IL1B protein_coding 7.3
bar=donor   line=cohort median 		6.9 6.9 83.9%
4 CXCL8 protein_coding 10.9
bar=donor   line=cohort median 		7.6 7.6 99.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.2
bar=donor   line=cohort median 		4.0 4.0 25.0%
6 FCGR3B protein_coding 11.8
bar=donor   line=cohort median 		11.3 11.3 80.5%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.1
bar=donor   line=cohort median 		10.9 10.9 7.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.3
bar=donor   line=cohort median 		5.3 5.3 54.5%
9 CD3E protein_coding 2.2
bar=donor   line=cohort median 		2.6 2.6 27.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.8
bar=donor   line=cohort median 		6.3 6.3 16.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.3
bar=donor   line=cohort median 		3.4 3.4 42.8%
12 GNLY protein_coding 4.8
bar=donor   line=cohort median 		4.9 4.9 46.2%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 11.8
bar=donor   line=cohort median 		6.6 6.6 92.8%
14 HBA1 protein_coding 5.4
bar=donor   line=cohort median 		2.6 2.6 79.8%
15 HBA2 protein_coding 10.4
bar=donor   line=cohort median 		5.6 5.6 91.4%
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