GSM5528583

Dataset: gse182409 • Sample: T087 • Status: Pregnancy-stage cohort
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Quality Control Metrics

75,356,694 Total counts Group median: 70,855,220 • 58.6%ile (≈ Median)
32,129 Detected genes Group median: 31,576 • 63.4%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 14.0%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

70.3Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.06
bar=donor   line=cohort median 		9.31 30.0%
CETP Lipid Metabolism 1.29
bar=donor   line=cohort median 		1.18 56.9%
SIRT6 Sirtuin Family 3.00
bar=donor   line=cohort median 		2.22 99.7%
SIRT1 Sirtuin Family 5.97
bar=donor   line=cohort median 		5.50 99.7%
SIRT3 Sirtuin Family 2.33
bar=donor   line=cohort median 		2.33 52.8%
IGF1R Insulin/IGF-1 Signaling 7.17
bar=donor   line=cohort median 		7.09 58.3%
KLOTHO Anti-aging 1.19
bar=donor   line=cohort median 		0.66 82.4%
IRS2 Insulin/IGF-1 Signaling 6.27
bar=donor   line=cohort median 		5.59 94.1%
TP53 Tumor Suppression 2.72
bar=donor   line=cohort median 		2.72 50.7%
SHC1 Signal Transduction 4.16
bar=donor   line=cohort median 		3.95 78.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000258486 ENSG00000258486 15.7 3,168,363
2 ENSG00000265150 ENSG00000265150 15.6 2,900,048
3 7SK ENSG00000202198 misc_RNA 14.7 1,640,431
4 S100A9 ENSG00000163220 protein_coding 13.7 804,962
5 B2M ENSG00000166710 protein_coding 13.7 796,992
6 AL355075.4 ENSG00000259001 lncRNA 13.7 779,775
7 MALAT1 ENSG00000251562 lncRNA 13.6 765,527
8 NAMPT ENSG00000105835 protein_coding 13.3 596,426
9 ALAS2 ENSG00000158578 protein_coding 13.2 560,492
10 BNIP3L ENSG00000104765 protein_coding 12.8 441,147

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.8
bar=donor   line=cohort median 		11.8 11.8 99.0%
2 S100A9 protein_coding 13.7
bar=donor   line=cohort median 		13.1 13.1 93.5%
3 IL1B protein_coding 6.6
bar=donor   line=cohort median 		6.9 6.9 38.0%
4 CXCL8 protein_coding 8.9
bar=donor   line=cohort median 		7.6 7.6 92.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.3
bar=donor   line=cohort median 		4.0 4.0 84.6%
6 FCGR3B protein_coding 11.8
bar=donor   line=cohort median 		11.3 11.3 83.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.6
bar=donor   line=cohort median 		10.9 10.9 93.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.1
bar=donor   line=cohort median 		5.3 5.3 35.3%
9 CD3E protein_coding 1.4
bar=donor   line=cohort median 		2.6 2.6 3.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.7
bar=donor   line=cohort median 		6.3 6.3 12.0%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.3
bar=donor   line=cohort median 		3.4 3.4 46.2%
12 GNLY protein_coding 4.4
bar=donor   line=cohort median 		4.9 4.9 22.9%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 9.2
bar=donor   line=cohort median 		6.6 6.6 81.2%
14 HBA1 protein_coding 3.1
bar=donor   line=cohort median 		2.6 2.6 57.2%
15 HBA2 protein_coding 7.7
bar=donor   line=cohort median 		5.6 5.6 70.9%
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