GSM5528584

Dataset: gse182409 • Sample: T088 • Status: Pregnancy-stage cohort
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Quality Control Metrics

89,432,837 Total counts Group median: 70,855,220 • 88.7%ile (↑ High)
27,943 Detected genes Group median: 31,576 • 16.1%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 20.9%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

47.8Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.67
bar=donor   line=cohort median 		9.31 78.3%
CETP Lipid Metabolism 0.84
bar=donor   line=cohort median 		1.18 25.2%
SIRT6 Sirtuin Family 2.39
bar=donor   line=cohort median 		2.22 76.2%
SIRT1 Sirtuin Family 5.82
bar=donor   line=cohort median 		5.50 94.8%
SIRT3 Sirtuin Family 2.00
bar=donor   line=cohort median 		2.33 8.6%
IGF1R Insulin/IGF-1 Signaling 6.77
bar=donor   line=cohort median 		7.09 20.3%
KLOTHO Anti-aging 1.47
bar=donor   line=cohort median 		0.66 94.1%
IRS2 Insulin/IGF-1 Signaling 5.55
bar=donor   line=cohort median 		5.59 43.1%
TP53 Tumor Suppression 2.21
bar=donor   line=cohort median 		2.72 19.7%
SHC1 Signal Transduction 3.75
bar=donor   line=cohort median 		3.95 17.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.6 1,717,993
2 B2M ENSG00000166710 protein_coding 13.8 966,035
3 ENSG00000258486 ENSG00000258486 13.6 821,263
4 S100A9 ENSG00000163220 protein_coding 13.5 785,225
5 AL355075.4 ENSG00000259001 lncRNA 13.1 596,685
6 ENSG00000266037 ENSG00000266037 12.9 523,821
7 MALAT1 ENSG00000251562 lncRNA 12.9 521,749
8 ENSG00000265150 ENSG00000265150 12.8 478,463
9 NAMPT ENSG00000105835 protein_coding 12.7 448,658
10 SOD2 ENSG00000112096 protein_coding 12.6 409,178

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.3
bar=donor   line=cohort median 		11.8 11.8 87.3%
2 S100A9 protein_coding 13.5
bar=donor   line=cohort median 		13.1 13.1 83.9%
3 IL1B protein_coding 7.6
bar=donor   line=cohort median 		6.9 6.9 94.9%
4 CXCL8 protein_coding 6.9
bar=donor   line=cohort median 		7.6 7.6 32.5%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.3
bar=donor   line=cohort median 		4.0 4.0 61.3%
6 FCGR3B protein_coding 12.3
bar=donor   line=cohort median 		11.3 11.3 96.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.0
bar=donor   line=cohort median 		10.9 10.9 63.4%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 6.0
bar=donor   line=cohort median 		5.3 5.3 96.9%
9 CD3E protein_coding 2.6
bar=donor   line=cohort median 		2.6 2.6 47.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.0
bar=donor   line=cohort median 		6.3 6.3 29.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.4
bar=donor   line=cohort median 		3.4 3.4 47.6%
12 GNLY protein_coding 5.3
bar=donor   line=cohort median 		4.9 4.9 77.7%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 9.4
bar=donor   line=cohort median 		6.6 6.6 83.2%
14 HBA1 protein_coding 7.3
bar=donor   line=cohort median 		2.6 2.6 92.1%
15 HBA2 protein_coding 10.0
bar=donor   line=cohort median 		5.6 5.6 90.1%
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