GSM5528587

Dataset: gse182409 • Sample: T091 • Status: Pregnancy-stage cohort
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Quality Control Metrics

81,462,828 Total counts Group median: 70,855,220 • 72.9%ile (≈ Median)
26,364 Detected genes Group median: 31,576 • 3.8%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 33.2%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

33.9Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.60
bar=donor   line=cohort median 		9.31 5.2%
CETP Lipid Metabolism 1.44
bar=donor   line=cohort median 		1.18 69.3%
SIRT6 Sirtuin Family 1.84
bar=donor   line=cohort median 		2.22 12.1%
SIRT1 Sirtuin Family 5.45
bar=donor   line=cohort median 		5.50 34.1%
SIRT3 Sirtuin Family 1.59
bar=donor   line=cohort median 		2.33 0.3%
IGF1R Insulin/IGF-1 Signaling 6.79
bar=donor   line=cohort median 		7.09 23.1%
KLOTHO Anti-aging 1.40
bar=donor   line=cohort median 		0.66 92.1%
IRS2 Insulin/IGF-1 Signaling 5.08
bar=donor   line=cohort median 		5.59 14.8%
TP53 Tumor Suppression 2.26
bar=donor   line=cohort median 		2.72 24.5%
SHC1 Signal Transduction 4.04
bar=donor   line=cohort median 		3.95 63.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.5 3,057,136
2 ENSG00000258486 ENSG00000258486 15.3 2,606,689
3 7SK ENSG00000202198 misc_RNA 15.0 2,083,887
4 B2M ENSG00000166710 protein_coding 13.9 1,020,640
5 S100A9 ENSG00000163220 protein_coding 13.9 965,321
6 AL355075.4 ENSG00000259001 lncRNA 13.8 945,049
7 NAMPT ENSG00000105835 protein_coding 13.1 582,808
8 ALAS2 ENSG00000158578 protein_coding 13.0 526,968
9 MALAT1 ENSG00000251562 lncRNA 13.0 523,314
10 BNIP3L ENSG00000104765 protein_coding 12.8 454,317

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.6
bar=donor   line=cohort median 		11.8 11.8 94.9%
2 S100A9 protein_coding 13.9
bar=donor   line=cohort median 		13.1 13.1 98.3%
3 IL1B protein_coding 6.2
bar=donor   line=cohort median 		6.9 6.9 15.4%
4 CXCL8 protein_coding 10.1
bar=donor   line=cohort median 		7.6 7.6 98.3%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.3
bar=donor   line=cohort median 		4.0 4.0 62.7%
6 FCGR3B protein_coding 11.2
bar=donor   line=cohort median 		11.3 11.3 42.1%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.6
bar=donor   line=cohort median 		10.9 10.9 29.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.6
bar=donor   line=cohort median 		5.3 5.3 79.8%
9 CD3E protein_coding 2.4
bar=donor   line=cohort median 		2.6 2.6 37.3%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.7
bar=donor   line=cohort median 		6.3 6.3 14.7%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.3
bar=donor   line=cohort median 		3.4 3.4 84.6%
12 GNLY protein_coding 6.2
bar=donor   line=cohort median 		4.9 4.9 98.3%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 8.8
bar=donor   line=cohort median 		6.6 6.6 75.0%
14 HBA1 protein_coding 2.9
bar=donor   line=cohort median 		2.6 2.6 53.8%
15 HBA2 protein_coding 5.6
bar=donor   line=cohort median 		5.6 5.6 49.7%
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