GSM5528588

Dataset: gse182409 • Sample: T092 • Status: Pregnancy-stage cohort
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Quality Control Metrics

63,720,417 Total counts Group median: 70,855,220 • 29.1%ile (≈ Median)
27,558 Detected genes Group median: 31,576 • 11.3%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 6.5%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

53.2Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.47
bar=donor   line=cohort median 		9.31 63.8%
CETP Lipid Metabolism 1.12
bar=donor   line=cohort median 		1.18 44.5%
SIRT6 Sirtuin Family 2.41
bar=donor   line=cohort median 		2.22 78.3%
SIRT1 Sirtuin Family 5.52
bar=donor   line=cohort median 		5.50 54.8%
SIRT3 Sirtuin Family 2.43
bar=donor   line=cohort median 		2.33 65.9%
IGF1R Insulin/IGF-1 Signaling 6.72
bar=donor   line=cohort median 		7.09 17.6%
KLOTHO Anti-aging 0.56
bar=donor   line=cohort median 		0.66 39.0%
IRS2 Insulin/IGF-1 Signaling 5.74
bar=donor   line=cohort median 		5.59 63.1%
TP53 Tumor Suppression 2.30
bar=donor   line=cohort median 		2.72 27.2%
SHC1 Signal Transduction 4.16
bar=donor   line=cohort median 		3.95 77.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.4 1,193,261
2 ENSG00000258486 ENSG00000258486 14.1 971,820
3 ENSG00000265150 ENSG00000265150 14.1 944,771
4 ALAS2 ENSG00000158578 protein_coding 13.9 814,842
5 B2M ENSG00000166710 protein_coding 13.7 742,671
6 S100A9 ENSG00000163220 protein_coding 13.2 519,932
7 MALAT1 ENSG00000251562 lncRNA 13.1 489,130
8 NAMPT ENSG00000105835 protein_coding 12.9 425,609
9 AL355075.4 ENSG00000259001 lncRNA 12.9 408,471
10 BNIP3L ENSG00000104765 protein_coding 12.8 382,247

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.0
bar=donor   line=cohort median 		11.8 11.8 65.4%
2 S100A9 protein_coding 13.2
bar=donor   line=cohort median 		13.1 13.1 64.0%
3 IL1B protein_coding 7.5
bar=donor   line=cohort median 		6.9 6.9 90.8%
4 CXCL8 protein_coding 8.5
bar=donor   line=cohort median 		7.6 7.6 82.5%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.4
bar=donor   line=cohort median 		4.0 4.0 63.4%
6 FCGR3B protein_coding 12.4
bar=donor   line=cohort median 		11.3 11.3 98.3%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.1
bar=donor   line=cohort median 		10.9 10.9 68.2%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.5
bar=donor   line=cohort median 		5.3 5.3 71.6%
9 CD3E protein_coding 1.7
bar=donor   line=cohort median 		2.6 2.6 10.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.1
bar=donor   line=cohort median 		6.3 6.3 39.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.0
bar=donor   line=cohort median 		3.4 3.4 28.4%
12 GNLY protein_coding 4.9
bar=donor   line=cohort median 		4.9 4.9 53.8%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.7
bar=donor   line=cohort median 		6.6 6.6 29.8%
14 HBA1 protein_coding 2.5
bar=donor   line=cohort median 		2.6 2.6 47.6%
15 HBA2 protein_coding 5.5
bar=donor   line=cohort median 		5.6 5.6 46.9%
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