GSM5528590

Dataset: gse182409 • Sample: T094 • Status: Pregnancy-stage cohort
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Quality Control Metrics

72,646,863 Total counts Group median: 70,855,220 • 55.8%ile (≈ Median)
33,650 Detected genes Group median: 31,576 • 94.9%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 62.0%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

39.0Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.23
bar=donor   line=cohort median 		9.31 46.6%
CETP Lipid Metabolism 1.80
bar=donor   line=cohort median 		1.18 83.8%
SIRT6 Sirtuin Family 2.29
bar=donor   line=cohort median 		2.22 62.4%
SIRT1 Sirtuin Family 5.68
bar=donor   line=cohort median 		5.50 86.6%
SIRT3 Sirtuin Family 1.95
bar=donor   line=cohort median 		2.33 4.5%
IGF1R Insulin/IGF-1 Signaling 6.71
bar=donor   line=cohort median 		7.09 16.9%
KLOTHO Anti-aging 0.87
bar=donor   line=cohort median 		0.66 63.1%
IRS2 Insulin/IGF-1 Signaling 4.76
bar=donor   line=cohort median 		5.59 6.6%
TP53 Tumor Suppression 1.83
bar=donor   line=cohort median 		2.72 3.8%
SHC1 Signal Transduction 3.73
bar=donor   line=cohort median 		3.95 15.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.5 1,641,372
2 ENSG00000258486 ENSG00000258486 14.3 1,496,313
3 7SK ENSG00000202198 misc_RNA 13.9 1,100,511
4 MALAT1 ENSG00000251562 lncRNA 13.4 791,229
5 B2M ENSG00000166710 protein_coding 13.2 690,749
6 S100A9 ENSG00000163220 protein_coding 13.0 586,243
7 NAMPT ENSG00000105835 protein_coding 12.9 565,055
8 AL355075.4 ENSG00000259001 lncRNA 12.6 467,317
9 EEF1A1 ENSG00000156508 protein_coding 12.3 381,338
10 SOD2 ENSG00000112096 protein_coding 12.3 358,792

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.6
bar=donor   line=cohort median 		11.8 11.8 36.0%
2 S100A9 protein_coding 13.0
bar=donor   line=cohort median 		13.1 13.1 41.4%
3 IL1B protein_coding 6.5
bar=donor   line=cohort median 		6.9 6.9 29.8%
4 CXCL8 protein_coding 8.8
bar=donor   line=cohort median 		7.6 7.6 90.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.5
bar=donor   line=cohort median 		4.0 4.0 34.6%
6 FCGR3B protein_coding 11.1
bar=donor   line=cohort median 		11.3 11.3 31.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.5
bar=donor   line=cohort median 		10.9 10.9 23.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.1
bar=donor   line=cohort median 		5.3 5.3 25.7%
9 CD3E protein_coding 3.1
bar=donor   line=cohort median 		2.6 2.6 76.4%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 7.2
bar=donor   line=cohort median 		6.3 6.3 97.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.8
bar=donor   line=cohort median 		3.4 3.4 64.7%
12 GNLY protein_coding 5.0
bar=donor   line=cohort median 		4.9 4.9 57.9%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 4.4
bar=donor   line=cohort median 		6.6 6.6 4.5%
14 HBA1 protein_coding -1.1
bar=donor   line=cohort median 		2.6 2.6 3.1%
15 HBA2 protein_coding 2.0
bar=donor   line=cohort median 		5.6 5.6 3.1%
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