GSM5528591

Dataset: gse182409 • Sample: T095 • Status: Pregnancy-stage cohort

Quality Control Metrics

70,498,152 Total counts Group median: 70,855,220 • 48.3%ile (≈ Median)
31,648 Detected genes Group median: 31,576 • 51.7%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 7.2%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

57.0Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.03
bar=donor   line=cohort median
9.31 25.9%
CETP Lipid Metabolism 0.68
bar=donor   line=cohort median
1.18 16.9%
SIRT6 Sirtuin Family 2.31
bar=donor   line=cohort median
2.22 66.6%
SIRT1 Sirtuin Family 5.57
bar=donor   line=cohort median
5.50 63.1%
SIRT3 Sirtuin Family 2.43
bar=donor   line=cohort median
2.33 67.2%
IGF1R Insulin/IGF-1 Signaling 7.45
bar=donor   line=cohort median
7.09 86.6%
KLOTHO Anti-aging 0.11
bar=donor   line=cohort median
0.66 17.6%
IRS2 Insulin/IGF-1 Signaling 6.01
bar=donor   line=cohort median
5.59 85.2%
TP53 Tumor Suppression 3.37
bar=donor   line=cohort median
2.72 87.9%
SHC1 Signal Transduction 3.98
bar=donor   line=cohort median
3.95 53.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.6 3,086,614
2 ENSG00000258486 ENSG00000258486 15.6 3,032,445
3 7SK ENSG00000202198 misc_RNA 15.0 2,028,720
4 AL355075.4 ENSG00000259001 lncRNA 13.7 786,649
5 S100A9 ENSG00000163220 protein_coding 13.5 723,367
6 B2M ENSG00000166710 protein_coding 13.4 656,869
7 MALAT1 ENSG00000251562 lncRNA 13.3 619,585
8 ALAS2 ENSG00000158578 protein_coding 13.2 574,880
9 NAMPT ENSG00000105835 protein_coding 12.7 404,823
10 SLC25A37 ENSG00000147454 protein_coding 12.6 382,451

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.2
bar=donor   line=cohort median
11.8 11.8 79.8%
2 S100A9 protein_coding 13.5
bar=donor   line=cohort median
13.1 13.1 85.3%
3 IL1B protein_coding 7.4
bar=donor   line=cohort median
6.9 6.9 87.3%
4 CXCL8 protein_coding 7.7
bar=donor   line=cohort median
7.6 7.6 57.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.7
bar=donor   line=cohort median
4.0 4.0 39.4%
6 FCGR3B protein_coding 11.7
bar=donor   line=cohort median
11.3 11.3 77.7%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.9
bar=donor   line=cohort median
10.9 10.9 51.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.2
bar=donor   line=cohort median
5.3 5.3 43.5%
9 CD3E protein_coding 2.2
bar=donor   line=cohort median
2.6 2.6 29.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.3
bar=donor   line=cohort median
6.3 6.3 49.7%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.3
bar=donor   line=cohort median
3.4 3.4 4.5%
12 GNLY protein_coding 4.3
bar=donor   line=cohort median
4.9 4.9 20.9%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 6.6
bar=donor   line=cohort median
6.6 6.6 47.6%
14 HBA1 protein_coding 1.0
bar=donor   line=cohort median
2.6 2.6 31.2%
15 HBA2 protein_coding 4.9
bar=donor   line=cohort median
5.6 5.6 42.1%