GSM5528595

Dataset: gse182409 • Sample: T099 • Status: Pregnancy-stage cohort
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Quality Control Metrics

95,184,663 Total counts Group median: 70,855,220 • 93.5%ile (↑ High)
32,608 Detected genes Group median: 31,576 • 74.3%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 72.3%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

42.7Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.59
bar=donor   line=cohort median 		9.31 72.1%
CETP Lipid Metabolism 0.01
bar=donor   line=cohort median 		1.18 1.7%
SIRT6 Sirtuin Family 1.94
bar=donor   line=cohort median 		2.22 18.3%
SIRT1 Sirtuin Family 5.30
bar=donor   line=cohort median 		5.50 8.6%
SIRT3 Sirtuin Family 2.33
bar=donor   line=cohort median 		2.33 51.4%
IGF1R Insulin/IGF-1 Signaling 7.52
bar=donor   line=cohort median 		7.09 90.7%
KLOTHO Anti-aging 1.39
bar=donor   line=cohort median 		0.66 90.7%
IRS2 Insulin/IGF-1 Signaling 5.43
bar=donor   line=cohort median 		5.59 33.5%
TP53 Tumor Suppression 2.21
bar=donor   line=cohort median 		2.72 20.3%
SHC1 Signal Transduction 3.86
bar=donor   line=cohort median 		3.95 39.7%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.6 4,348,513
2 ENSG00000258486 ENSG00000258486 15.3 3,624,246
3 7SK ENSG00000202198 misc_RNA 14.3 1,830,721
4 B2M ENSG00000166710 protein_coding 13.4 937,374
5 AL355075.4 ENSG00000259001 lncRNA 13.0 739,161
6 ALAS2 ENSG00000158578 protein_coding 12.9 677,995
7 S100A9 ENSG00000163220 protein_coding 12.9 673,409
8 MALAT1 ENSG00000251562 lncRNA 12.9 658,027
9 BNIP3L ENSG00000104765 protein_coding 12.6 560,589
10 EPB41 ENSG00000159023 protein_coding 12.6 557,354

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.4
bar=donor   line=cohort median 		11.8 11.8 20.9%
2 S100A9 protein_coding 12.9
bar=donor   line=cohort median 		13.1 13.1 34.6%
3 IL1B protein_coding 6.7
bar=donor   line=cohort median 		6.9 6.9 41.4%
4 CXCL8 protein_coding 8.1
bar=donor   line=cohort median 		7.6 7.6 67.5%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.2
bar=donor   line=cohort median 		4.0 4.0 53.8%
6 FCGR3B protein_coding 11.3
bar=donor   line=cohort median 		11.3 11.3 44.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.0
bar=donor   line=cohort median 		10.9 10.9 61.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.3
bar=donor   line=cohort median 		5.3 5.3 49.7%
9 CD3E protein_coding 2.0
bar=donor   line=cohort median 		2.6 2.6 17.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.9
bar=donor   line=cohort median 		6.3 6.3 89.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.9
bar=donor   line=cohort median 		3.4 3.4 22.3%
12 GNLY protein_coding 4.8
bar=donor   line=cohort median 		4.9 4.9 44.9%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 4.1
bar=donor   line=cohort median 		6.6 6.6 1.7%
14 HBA1 protein_coding -0.5
bar=donor   line=cohort median 		2.6 2.6 11.3%
15 HBA2 protein_coding 2.4
bar=donor   line=cohort median 		5.6 5.6 6.5%
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