GSM5528598

Dataset: gse182409 • Sample: T102 • Status: Pregnancy-stage cohort
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Quality Control Metrics

67,207,607 Total counts Group median: 70,855,220 • 40.8%ile (≈ Median)
28,458 Detected genes Group median: 31,576 • 18.2%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 18.8%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

42.5Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.44
bar=donor   line=cohort median 		9.31 61.0%
CETP Lipid Metabolism 1.09
bar=donor   line=cohort median 		1.18 41.0%
SIRT6 Sirtuin Family 2.09
bar=donor   line=cohort median 		2.22 33.5%
SIRT1 Sirtuin Family 5.63
bar=donor   line=cohort median 		5.50 75.5%
SIRT3 Sirtuin Family 2.42
bar=donor   line=cohort median 		2.33 64.5%
IGF1R Insulin/IGF-1 Signaling 6.78
bar=donor   line=cohort median 		7.09 21.7%
KLOTHO Anti-aging 1.04
bar=donor   line=cohort median 		0.66 72.8%
IRS2 Insulin/IGF-1 Signaling 5.14
bar=donor   line=cohort median 		5.59 16.9%
TP53 Tumor Suppression 2.15
bar=donor   line=cohort median 		2.72 16.2%
SHC1 Signal Transduction 3.79
bar=donor   line=cohort median 		3.95 21.7%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000258486 ENSG00000258486 14.4 1,386,337
2 ENSG00000265150 ENSG00000265150 14.3 1,236,053
3 7SK ENSG00000202198 misc_RNA 14.0 1,009,952
4 B2M ENSG00000166710 protein_coding 13.6 781,274
5 MALAT1 ENSG00000251562 lncRNA 13.4 695,467
6 S100A9 ENSG00000163220 protein_coding 13.2 599,328
7 NAMPT ENSG00000105835 protein_coding 12.7 406,658
8 AL355075.4 ENSG00000259001 lncRNA 12.6 396,169
9 SOD2 ENSG00000112096 protein_coding 12.5 365,275
10 SORL1 ENSG00000137642 protein_coding 12.4 328,205

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.2
bar=donor   line=cohort median 		11.8 11.8 82.5%
2 S100A9 protein_coding 13.2
bar=donor   line=cohort median 		13.1 13.1 62.7%
3 IL1B protein_coding 7.1
bar=donor   line=cohort median 		6.9 6.9 71.6%
4 CXCL8 protein_coding 6.6
bar=donor   line=cohort median 		7.6 7.6 18.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 2.7
bar=donor   line=cohort median 		4.0 4.0 19.5%
6 FCGR3B protein_coding 11.8
bar=donor   line=cohort median 		11.3 11.3 86.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.5
bar=donor   line=cohort median 		10.9 10.9 24.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.3
bar=donor   line=cohort median 		5.3 5.3 56.5%
9 CD3E protein_coding 2.3
bar=donor   line=cohort median 		2.6 2.6 35.3%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 7.0
bar=donor   line=cohort median 		6.3 6.3 92.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.5
bar=donor   line=cohort median 		3.4 3.4 8.6%
12 GNLY protein_coding 4.7
bar=donor   line=cohort median 		4.9 4.9 36.6%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 6.0
bar=donor   line=cohort median 		6.6 6.6 37.3%
14 HBA1 protein_coding 5.5
bar=donor   line=cohort median 		2.6 2.6 81.2%
15 HBA2 protein_coding 8.1
bar=donor   line=cohort median 		5.6 5.6 76.4%
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