GSM5528599

Dataset: gse182409 • Sample: T103 • Status: Pregnancy-stage cohort
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Quality Control Metrics

67,744,931 Total counts Group median: 70,855,220 • 41.4%ile (≈ Median)
27,370 Detected genes Group median: 31,576 • 8.6%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 24.3%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

43.2Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.68
bar=donor   line=cohort median 		9.31 7.9%
CETP Lipid Metabolism 0.99
bar=donor   line=cohort median 		1.18 37.6%
SIRT6 Sirtuin Family 1.95
bar=donor   line=cohort median 		2.22 19.0%
SIRT1 Sirtuin Family 5.72
bar=donor   line=cohort median 		5.50 90.0%
SIRT3 Sirtuin Family 2.40
bar=donor   line=cohort median 		2.33 60.3%
IGF1R Insulin/IGF-1 Signaling 7.10
bar=donor   line=cohort median 		7.09 51.4%
KLOTHO Anti-aging 0.85
bar=donor   line=cohort median 		0.66 61.7%
IRS2 Insulin/IGF-1 Signaling 5.36
bar=donor   line=cohort median 		5.59 30.0%
TP53 Tumor Suppression 2.33
bar=donor   line=cohort median 		2.72 29.3%
SHC1 Signal Transduction 3.91
bar=donor   line=cohort median 		3.95 45.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 15.2 2,247,773
2 ENSG00000265150 ENSG00000265150 14.1 1,055,413
3 ENSG00000258486 ENSG00000258486 14.1 1,045,798
4 AL355075.4 ENSG00000259001 lncRNA 13.9 933,791
5 B2M ENSG00000166710 protein_coding 13.8 864,794
6 MALAT1 ENSG00000251562 lncRNA 13.7 794,045
7 S100A9 ENSG00000163220 protein_coding 13.6 741,090
8 NAMPT ENSG00000105835 protein_coding 13.0 501,681
9 ALAS2 ENSG00000158578 protein_coding 12.5 354,704
10 SOD2 ENSG00000112096 protein_coding 12.5 351,339

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.4
bar=donor   line=cohort median 		11.8 11.8 91.4%
2 S100A9 protein_coding 13.6
bar=donor   line=cohort median 		13.1 13.1 89.4%
3 IL1B protein_coding 5.9
bar=donor   line=cohort median 		6.9 6.9 6.5%
4 CXCL8 protein_coding 7.5
bar=donor   line=cohort median 		7.6 7.6 49.0%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.7
bar=donor   line=cohort median 		4.0 4.0 67.5%
6 FCGR3B protein_coding 11.3
bar=donor   line=cohort median 		11.3 11.3 47.6%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.8
bar=donor   line=cohort median 		10.9 10.9 42.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.3
bar=donor   line=cohort median 		5.3 5.3 55.1%
9 CD3E protein_coding 2.4
bar=donor   line=cohort median 		2.6 2.6 40.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.1
bar=donor   line=cohort median 		6.3 6.3 41.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.2
bar=donor   line=cohort median 		3.4 3.4 83.2%
12 GNLY protein_coding 5.1
bar=donor   line=cohort median 		4.9 4.9 62.0%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 6.5
bar=donor   line=cohort median 		6.6 6.6 45.5%
14 HBA1 protein_coding 0.5
bar=donor   line=cohort median 		2.6 2.6 26.4%
15 HBA2 protein_coding 3.1
bar=donor   line=cohort median 		5.6 5.6 18.2%
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