GSM5528600

Dataset: gse182409 • Sample: T104 • Status: Pregnancy-stage cohort
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Quality Control Metrics

61,107,695 Total counts Group median: 70,855,220 • 23.6%ile (↓ Low)
32,039 Detected genes Group median: 31,576 • 59.2%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 32.5%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

48.9Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.39
bar=donor   line=cohort median 		9.31 54.1%
CETP Lipid Metabolism 1.34
bar=donor   line=cohort median 		1.18 62.4%
SIRT6 Sirtuin Family 2.10
bar=donor   line=cohort median 		2.22 36.2%
SIRT1 Sirtuin Family 5.31
bar=donor   line=cohort median 		5.50 10.7%
SIRT3 Sirtuin Family 2.26
bar=donor   line=cohort median 		2.33 40.3%
IGF1R Insulin/IGF-1 Signaling 7.03
bar=donor   line=cohort median 		7.09 44.5%
KLOTHO Anti-aging 0.37
bar=donor   line=cohort median 		0.66 24.5%
IRS2 Insulin/IGF-1 Signaling 6.91
bar=donor   line=cohort median 		5.59 99.7%
TP53 Tumor Suppression 2.49
bar=donor   line=cohort median 		2.72 37.6%
SHC1 Signal Transduction 4.18
bar=donor   line=cohort median 		3.95 79.0%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000258486 ENSG00000258486 15.0 1,869,483
2 ENSG00000265150 ENSG00000265150 15.0 1,823,844
3 7SK ENSG00000202198 misc_RNA 14.8 1,541,382
4 S100A9 ENSG00000163220 protein_coding 13.7 741,110
5 B2M ENSG00000166710 protein_coding 13.6 707,010
6 AL355075.4 ENSG00000259001 lncRNA 13.6 662,623
7 MALAT1 ENSG00000251562 lncRNA 13.3 568,431
8 ALAS2 ENSG00000158578 protein_coding 13.1 478,649
9 NAMPT ENSG00000105835 protein_coding 13.1 470,557
10 S100A8 ENSG00000143546 protein_coding 12.6 336,512

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.6
bar=donor   line=cohort median 		11.8 11.8 95.5%
2 S100A9 protein_coding 13.7
bar=donor   line=cohort median 		13.1 13.1 92.8%
3 IL1B protein_coding 6.4
bar=donor   line=cohort median 		6.9 6.9 25.0%
4 CXCL8 protein_coding 8.1
bar=donor   line=cohort median 		7.6 7.6 68.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.5
bar=donor   line=cohort median 		4.0 4.0 88.7%
6 FCGR3B protein_coding 11.4
bar=donor   line=cohort median 		11.3 11.3 58.6%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.7
bar=donor   line=cohort median 		10.9 10.9 97.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.4
bar=donor   line=cohort median 		5.3 5.3 59.2%
9 CD3E protein_coding 2.1
bar=donor   line=cohort median 		2.6 2.6 24.3%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.1
bar=donor   line=cohort median 		6.3 6.3 36.0%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.3
bar=donor   line=cohort median 		3.4 3.4 43.5%
12 GNLY protein_coding 3.8
bar=donor   line=cohort median 		4.9 4.9 3.8%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 4.6
bar=donor   line=cohort median 		6.6 6.6 7.2%
14 HBA1 protein_coding -0.6
bar=donor   line=cohort median 		2.6 2.6 9.2%
15 HBA2 protein_coding 2.2
bar=donor   line=cohort median 		5.6 5.6 5.8%
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