GSM5528601

Dataset: gse182409 • Sample: T105 • Status: Pregnancy-stage cohort
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Quality Control Metrics

57,620,504 Total counts Group median: 70,855,220 • 18.2%ile (↓ Low)
31,447 Detected genes Group median: 31,576 • 46.9%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 37.3%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

29.9Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.79
bar=donor   line=cohort median 		9.31 12.8%
CETP Lipid Metabolism 1.09
bar=donor   line=cohort median 		1.18 40.3%
SIRT6 Sirtuin Family 1.71
bar=donor   line=cohort median 		2.22 2.4%
SIRT1 Sirtuin Family 5.52
bar=donor   line=cohort median 		5.50 55.5%
SIRT3 Sirtuin Family 2.12
bar=donor   line=cohort median 		2.33 21.0%
IGF1R Insulin/IGF-1 Signaling 6.34
bar=donor   line=cohort median 		7.09 4.5%
KLOTHO Anti-aging 1.37
bar=donor   line=cohort median 		0.66 90.0%
IRS2 Insulin/IGF-1 Signaling 5.62
bar=donor   line=cohort median 		5.59 52.8%
TP53 Tumor Suppression 2.11
bar=donor   line=cohort median 		2.72 14.1%
SHC1 Signal Transduction 3.59
bar=donor   line=cohort median 		3.95 5.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.6 1,224,414
2 ENSG00000265150 ENSG00000265150 14.3 1,048,069
3 ENSG00000258486 ENSG00000258486 14.1 909,159
4 S100A9 ENSG00000163220 protein_coding 13.8 714,081
5 B2M ENSG00000166710 protein_coding 13.7 659,203
6 AL355075.4 ENSG00000259001 lncRNA 13.4 538,721
7 MALAT1 ENSG00000251562 lncRNA 13.4 537,086
8 NAMPT ENSG00000105835 protein_coding 13.2 492,840
9 S100A8 ENSG00000143546 protein_coding 12.7 327,360
10 SOD2 ENSG00000112096 protein_coding 12.4 281,773

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.7
bar=donor   line=cohort median 		11.8 11.8 96.9%
2 S100A9 protein_coding 13.8
bar=donor   line=cohort median 		13.1 13.1 95.5%
3 IL1B protein_coding 7.0
bar=donor   line=cohort median 		6.9 6.9 62.0%
4 CXCL8 protein_coding 7.8
bar=donor   line=cohort median 		7.6 7.6 62.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.0
bar=donor   line=cohort median 		4.0 4.0 49.0%
6 FCGR3B protein_coding 11.9
bar=donor   line=cohort median 		11.3 11.3 87.3%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.6
bar=donor   line=cohort median 		10.9 10.9 96.2%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.1
bar=donor   line=cohort median 		5.3 5.3 22.3%
9 CD3E protein_coding 2.0
bar=donor   line=cohort median 		2.6 2.6 18.2%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.7
bar=donor   line=cohort median 		6.3 6.3 9.2%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.5
bar=donor   line=cohort median 		3.4 3.4 9.9%
12 GNLY protein_coding 4.0
bar=donor   line=cohort median 		4.9 4.9 7.9%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 4.5
bar=donor   line=cohort median 		6.6 6.6 5.1%
14 HBA1 protein_coding -1.1
bar=donor   line=cohort median 		2.6 2.6 3.8%
15 HBA2 protein_coding 2.7
bar=donor   line=cohort median 		5.6 5.6 10.6%
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