GSM5528602

Dataset: gse182409 • Sample: T106 • Status: Pregnancy-stage cohort
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Quality Control Metrics

64,845,842 Total counts Group median: 70,855,220 • 33.2%ile (≈ Median)
33,221 Detected genes Group median: 31,576 • 86.0%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 51.0%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

47.5Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.40
bar=donor   line=cohort median 		9.31 55.5%
CETP Lipid Metabolism 0.66
bar=donor   line=cohort median 		1.18 16.2%
SIRT6 Sirtuin Family 2.25
bar=donor   line=cohort median 		2.22 54.8%
SIRT1 Sirtuin Family 5.82
bar=donor   line=cohort median 		5.50 95.5%
SIRT3 Sirtuin Family 2.30
bar=donor   line=cohort median 		2.33 47.2%
IGF1R Insulin/IGF-1 Signaling 6.95
bar=donor   line=cohort median 		7.09 37.6%
KLOTHO Anti-aging 0.90
bar=donor   line=cohort median 		0.66 65.9%
IRS2 Insulin/IGF-1 Signaling 5.86
bar=donor   line=cohort median 		5.59 74.1%
TP53 Tumor Suppression 2.28
bar=donor   line=cohort median 		2.72 25.9%
SHC1 Signal Transduction 3.49
bar=donor   line=cohort median 		3.95 1.7%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.7 1,624,539
2 ENSG00000258486 ENSG00000258486 14.4 1,378,489
3 MALAT1 ENSG00000251562 lncRNA 13.9 939,810
4 7SK ENSG00000202198 misc_RNA 13.6 799,413
5 HBB ENSG00000244734 protein_coding 13.0 521,243
6 B2M ENSG00000166710 protein_coding 12.7 420,074
7 S100A9 ENSG00000163220 protein_coding 12.7 405,383
8 AL355075.4 ENSG00000259001 lncRNA 12.5 365,298
9 NAMPT ENSG00000105835 protein_coding 12.4 347,126
10 SORL1 ENSG00000137642 protein_coding 12.2 299,077

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.3
bar=donor   line=cohort median 		11.8 11.8 18.8%
2 S100A9 protein_coding 12.7
bar=donor   line=cohort median 		13.1 13.1 18.2%
3 IL1B protein_coding 6.9
bar=donor   line=cohort median 		6.9 6.9 53.1%
4 CXCL8 protein_coding 7.5
bar=donor   line=cohort median 		7.6 7.6 49.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.1
bar=donor   line=cohort median 		4.0 4.0 51.7%
6 FCGR3B protein_coding 11.2
bar=donor   line=cohort median 		11.3 11.3 40.1%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.7
bar=donor   line=cohort median 		10.9 10.9 33.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.0
bar=donor   line=cohort median 		5.3 5.3 18.8%
9 CD3E protein_coding 3.4
bar=donor   line=cohort median 		2.6 2.6 86.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.1
bar=donor   line=cohort median 		6.3 6.3 40.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.5
bar=donor   line=cohort median 		3.4 3.4 51.7%
12 GNLY protein_coding 4.3
bar=donor   line=cohort median 		4.9 4.9 21.6%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 13.0
bar=donor   line=cohort median 		6.6 6.6 96.9%
14 HBA1 protein_coding 7.4
bar=donor   line=cohort median 		2.6 2.6 94.9%
15 HBA2 protein_coding 11.3
bar=donor   line=cohort median 		5.6 5.6 96.9%
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