GSM5528604

Dataset: gse182409 • Sample: T108 • Status: Pregnancy-stage cohort
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Quality Control Metrics

68,332,702 Total counts Group median: 70,855,220 • 43.5%ile (≈ Median)
33,598 Detected genes Group median: 31,576 • 92.8%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 70.2%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

68.1Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.57
bar=donor   line=cohort median 		9.31 3.8%
CETP Lipid Metabolism 1.86
bar=donor   line=cohort median 		1.18 87.2%
SIRT6 Sirtuin Family 2.38
bar=donor   line=cohort median 		2.22 72.1%
SIRT1 Sirtuin Family 5.51
bar=donor   line=cohort median 		5.50 52.1%
SIRT3 Sirtuin Family 2.76
bar=donor   line=cohort median 		2.33 92.1%
IGF1R Insulin/IGF-1 Signaling 7.48
bar=donor   line=cohort median 		7.09 89.3%
KLOTHO Anti-aging 0.65
bar=donor   line=cohort median 		0.66 48.6%
IRS2 Insulin/IGF-1 Signaling 6.01
bar=donor   line=cohort median 		5.59 85.9%
TP53 Tumor Suppression 3.23
bar=donor   line=cohort median 		2.72 81.7%
SHC1 Signal Transduction 4.07
bar=donor   line=cohort median 		3.95 67.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.8 1,884,866
2 ENSG00000258486 ENSG00000258486 14.7 1,745,819
3 7SK ENSG00000202198 misc_RNA 14.5 1,487,934
4 MALAT1 ENSG00000251562 lncRNA 14.0 1,081,393
5 B2M ENSG00000166710 protein_coding 13.5 748,966
6 AL355075.4 ENSG00000259001 lncRNA 13.0 531,759
7 S100A9 ENSG00000163220 protein_coding 12.9 504,169
8 NAMPT ENSG00000105835 protein_coding 12.8 471,287
9 NEAT1 ENSG00000245532 lncRNA 12.2 314,706
10 TMSB4X ENSG00000205542 protein_coding 12.2 310,685

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.5
bar=donor   line=cohort median 		11.8 11.8 27.7%
2 S100A9 protein_coding 12.9
bar=donor   line=cohort median 		13.1 13.1 36.0%
3 IL1B protein_coding 6.6
bar=donor   line=cohort median 		6.9 6.9 36.0%
4 CXCL8 protein_coding 7.7
bar=donor   line=cohort median 		7.6 7.6 55.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.1
bar=donor   line=cohort median 		4.0 4.0 24.3%
6 FCGR3B protein_coding 11.6
bar=donor   line=cohort median 		11.3 11.3 67.5%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.8
bar=donor   line=cohort median 		10.9 10.9 36.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.1
bar=donor   line=cohort median 		5.3 5.3 30.5%
9 CD3E protein_coding 2.9
bar=donor   line=cohort median 		2.6 2.6 64.0%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.8
bar=donor   line=cohort median 		6.3 6.3 81.2%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.7
bar=donor   line=cohort median 		3.4 3.4 61.3%
12 GNLY protein_coding 5.3
bar=donor   line=cohort median 		4.9 4.9 77.1%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 6.1
bar=donor   line=cohort median 		6.6 6.6 38.7%
14 HBA1 protein_coding 2.1
bar=donor   line=cohort median 		2.6 2.6 43.5%
15 HBA2 protein_coding 6.5
bar=donor   line=cohort median 		5.6 5.6 59.9%
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