GSM5528611

Dataset: gse182409 • Sample: T115 • Status: Pregnancy-stage cohort
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Quality Control Metrics

69,617,588 Total counts Group median: 70,855,220 • 47.6%ile (≈ Median)
31,054 Detected genes Group median: 31,576 • 43.5%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 43.5%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

56.7Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.51
bar=donor   line=cohort median 		9.31 1.7%
CETP Lipid Metabolism 1.31
bar=donor   line=cohort median 		1.18 60.3%
SIRT6 Sirtuin Family 2.18
bar=donor   line=cohort median 		2.22 45.2%
SIRT1 Sirtuin Family 5.54
bar=donor   line=cohort median 		5.50 61.0%
SIRT3 Sirtuin Family 2.57
bar=donor   line=cohort median 		2.33 83.1%
IGF1R Insulin/IGF-1 Signaling 7.14
bar=donor   line=cohort median 		7.09 55.5%
KLOTHO Anti-aging 0.67
bar=donor   line=cohort median 		0.66 51.4%
IRS2 Insulin/IGF-1 Signaling 5.88
bar=donor   line=cohort median 		5.59 78.3%
TP53 Tumor Suppression 3.26
bar=donor   line=cohort median 		2.72 83.1%
SHC1 Signal Transduction 3.93
bar=donor   line=cohort median 		3.95 47.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.5 1,597,398
2 ENSG00000265150 ENSG00000265150 14.2 1,223,621
3 ENSG00000258486 ENSG00000258486 14.1 1,144,411
4 B2M ENSG00000166710 protein_coding 13.8 974,439
5 MALAT1 ENSG00000251562 lncRNA 13.3 686,522
6 ALAS2 ENSG00000158578 protein_coding 13.2 631,568
7 S100A9 ENSG00000163220 protein_coding 13.1 601,325
8 AL355075.4 ENSG00000259001 lncRNA 13.0 532,345
9 SOD2 ENSG00000112096 protein_coding 12.5 397,486
10 NAMPT ENSG00000105835 protein_coding 12.5 374,795

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.7
bar=donor   line=cohort median 		11.8 11.8 44.9%
2 S100A9 protein_coding 13.1
bar=donor   line=cohort median 		13.1 13.1 51.0%
3 IL1B protein_coding 7.2
bar=donor   line=cohort median 		6.9 6.9 78.4%
4 CXCL8 protein_coding 6.6
bar=donor   line=cohort median 		7.6 7.6 19.5%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.1
bar=donor   line=cohort median 		4.0 4.0 77.1%
6 FCGR3B protein_coding 11.7
bar=donor   line=cohort median 		11.3 11.3 75.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.4
bar=donor   line=cohort median 		10.9 10.9 88.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.2
bar=donor   line=cohort median 		5.3 5.3 40.1%
9 CD3E protein_coding 2.0
bar=donor   line=cohort median 		2.6 2.6 16.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.5
bar=donor   line=cohort median 		6.3 6.3 63.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.6
bar=donor   line=cohort median 		3.4 3.4 55.1%
12 GNLY protein_coding 5.6
bar=donor   line=cohort median 		4.9 4.9 88.0%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 4.9
bar=donor   line=cohort median 		6.6 6.6 10.6%
14 HBA1 protein_coding -0.3
bar=donor   line=cohort median 		2.6 2.6 18.2%
15 HBA2 protein_coding 3.1
bar=donor   line=cohort median 		5.6 5.6 16.8%
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