GSM5528612

Dataset: gse182409 • Sample: T116 • Status: Pregnancy-stage cohort
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Quality Control Metrics

77,217,274 Total counts Group median: 70,855,220 • 63.4%ile (≈ Median)
32,212 Detected genes Group median: 31,576 • 65.4%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 30.5%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

54.3Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 10.01
bar=donor   line=cohort median 		9.31 90.7%
CETP Lipid Metabolism 2.21
bar=donor   line=cohort median 		1.18 93.5%
SIRT6 Sirtuin Family 2.51
bar=donor   line=cohort median 		2.22 87.9%
SIRT1 Sirtuin Family 5.56
bar=donor   line=cohort median 		5.50 61.7%
SIRT3 Sirtuin Family 2.31
bar=donor   line=cohort median 		2.33 47.9%
IGF1R Insulin/IGF-1 Signaling 6.64
bar=donor   line=cohort median 		7.09 12.8%
KLOTHO Anti-aging 0.48
bar=donor   line=cohort median 		0.66 32.1%
IRS2 Insulin/IGF-1 Signaling 4.33
bar=donor   line=cohort median 		5.59 1.0%
TP53 Tumor Suppression 2.59
bar=donor   line=cohort median 		2.72 43.1%
SHC1 Signal Transduction 4.13
bar=donor   line=cohort median 		3.95 72.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.1 2,369,520
2 ENSG00000258486 ENSG00000258486 14.8 2,024,573
3 7SK ENSG00000202198 misc_RNA 14.6 1,750,313
4 AL355075.4 ENSG00000259001 lncRNA 13.9 1,070,327
5 S100A9 ENSG00000163220 protein_coding 13.6 870,144
6 B2M ENSG00000166710 protein_coding 13.6 868,693
7 MALAT1 ENSG00000251562 lncRNA 13.3 696,794
8 NAMPT ENSG00000105835 protein_coding 12.6 425,063
9 ALAS2 ENSG00000158578 protein_coding 12.5 402,718
10 EEF1A1 ENSG00000156508 protein_coding 12.5 398,111

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.2
bar=donor   line=cohort median 		11.8 11.8 85.3%
2 S100A9 protein_coding 13.6
bar=donor   line=cohort median 		13.1 13.1 90.1%
3 IL1B protein_coding 6.6
bar=donor   line=cohort median 		6.9 6.9 32.5%
4 CXCL8 protein_coding 7.1
bar=donor   line=cohort median 		7.6 7.6 36.0%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.0
bar=donor   line=cohort median 		4.0 4.0 50.3%
6 FCGR3B protein_coding 11.8
bar=donor   line=cohort median 		11.3 11.3 84.6%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.6
bar=donor   line=cohort median 		10.9 10.9 25.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.8
bar=donor   line=cohort median 		5.3 5.3 89.4%
9 CD3E protein_coding 2.7
bar=donor   line=cohort median 		2.6 2.6 53.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.5
bar=donor   line=cohort median 		6.3 6.3 68.2%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.9
bar=donor   line=cohort median 		3.4 3.4 24.3%
12 GNLY protein_coding 5.1
bar=donor   line=cohort median 		4.9 4.9 63.4%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 7.4
bar=donor   line=cohort median 		6.6 6.6 58.6%
14 HBA1 protein_coding 0.2
bar=donor   line=cohort median 		2.6 2.6 22.3%
15 HBA2 protein_coding 4.7
bar=donor   line=cohort median 		5.6 5.6 38.7%
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