GSM5528614

Dataset: gse182409 • Sample: T118 • Status: Pregnancy-stage cohort
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Quality Control Metrics

85,620,629 Total counts Group median: 70,855,220 • 83.9%ile (↑ High)
31,471 Detected genes Group median: 31,576 • 47.6%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 90.8%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

44.6Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.75
bar=donor   line=cohort median 		9.31 11.4%
CETP Lipid Metabolism 1.17
bar=donor   line=cohort median 		1.18 48.6%
SIRT6 Sirtuin Family 2.28
bar=donor   line=cohort median 		2.22 60.3%
SIRT1 Sirtuin Family 5.79
bar=donor   line=cohort median 		5.50 92.8%
SIRT3 Sirtuin Family 2.08
bar=donor   line=cohort median 		2.33 16.2%
IGF1R Insulin/IGF-1 Signaling 6.94
bar=donor   line=cohort median 		7.09 36.2%
KLOTHO Anti-aging 0.70
bar=donor   line=cohort median 		0.66 53.5%
IRS2 Insulin/IGF-1 Signaling 5.82
bar=donor   line=cohort median 		5.59 71.4%
TP53 Tumor Suppression 2.32
bar=donor   line=cohort median 		2.72 27.9%
SHC1 Signal Transduction 3.81
bar=donor   line=cohort median 		3.95 27.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.8 4,109,487
2 ENSG00000258486 ENSG00000258486 15.0 2,283,491
3 7SK ENSG00000202198 misc_RNA 14.9 2,205,211
4 AL355075.4 ENSG00000259001 lncRNA 13.4 775,180
5 BNIP3L ENSG00000104765 protein_coding 13.4 745,552
6 B2M ENSG00000166710 protein_coding 13.4 741,951
7 MALAT1 ENSG00000251562 lncRNA 13.1 605,863
8 S100A9 ENSG00000163220 protein_coding 13.0 592,946
9 ALAS2 ENSG00000158578 protein_coding 13.0 582,029
10 SLC25A37 ENSG00000147454 protein_coding 12.8 516,460

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.5
bar=donor   line=cohort median 		11.8 11.8 28.4%
2 S100A9 protein_coding 13.0
bar=donor   line=cohort median 		13.1 13.1 42.8%
3 IL1B protein_coding 6.2
bar=donor   line=cohort median 		6.9 6.9 16.1%
4 CXCL8 protein_coding 8.5
bar=donor   line=cohort median 		7.6 7.6 81.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.9
bar=donor   line=cohort median 		4.0 4.0 73.6%
6 FCGR3B protein_coding 10.9
bar=donor   line=cohort median 		11.3 11.3 20.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.6
bar=donor   line=cohort median 		10.9 10.9 94.2%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.6
bar=donor   line=cohort median 		5.3 5.3 80.5%
9 CD3E protein_coding 2.3
bar=donor   line=cohort median 		2.6 2.6 34.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.6
bar=donor   line=cohort median 		6.3 6.3 6.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.6
bar=donor   line=cohort median 		3.4 3.4 59.2%
12 GNLY protein_coding 5.4
bar=donor   line=cohort median 		4.9 4.9 81.8%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 7.0
bar=donor   line=cohort median 		6.6 6.6 55.8%
14 HBA1 protein_coding 6.0
bar=donor   line=cohort median 		2.6 2.6 84.6%
15 HBA2 protein_coding 9.3
bar=donor   line=cohort median 		5.6 5.6 86.0%
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