GSM5528618

Dataset: gse182409 • Sample: T122 • Status: Pregnancy-stage cohort
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Quality Control Metrics

48,178,625 Total counts Group median: 70,855,220 • 5.1%ile (↓ Low)
27,399 Detected genes Group median: 31,576 • 9.2%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 63.4%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

49.5Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.60
bar=donor   line=cohort median 		9.31 73.5%
CETP Lipid Metabolism 0.70
bar=donor   line=cohort median 		1.18 17.6%
SIRT6 Sirtuin Family 2.28
bar=donor   line=cohort median 		2.22 61.0%
SIRT1 Sirtuin Family 5.41
bar=donor   line=cohort median 		5.50 25.2%
SIRT3 Sirtuin Family 2.06
bar=donor   line=cohort median 		2.33 14.1%
IGF1R Insulin/IGF-1 Signaling 7.41
bar=donor   line=cohort median 		7.09 83.1%
KLOTHO Anti-aging 0.66
bar=donor   line=cohort median 		0.66 50.0%
IRS2 Insulin/IGF-1 Signaling 6.08
bar=donor   line=cohort median 		5.59 87.9%
TP53 Tumor Suppression 2.27
bar=donor   line=cohort median 		2.72 25.2%
SHC1 Signal Transduction 4.00
bar=donor   line=cohort median 		3.95 56.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 13.9 795,460
2 MALAT1 ENSG00000251562 lncRNA 13.5 588,054
3 ENSG00000258486 ENSG00000258486 13.3 513,295
4 B2M ENSG00000166710 protein_coding 13.3 511,166
5 ENSG00000265150 ENSG00000265150 13.3 502,926
6 NAMPT ENSG00000105835 protein_coding 12.6 314,023
7 S100A9 ENSG00000163220 protein_coding 12.5 292,616
8 AL355075.4 ENSG00000259001 lncRNA 12.4 278,851
9 EEF1A1 ENSG00000156508 protein_coding 12.4 269,309
10 ALAS2 ENSG00000158578 protein_coding 12.3 254,969

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.5
bar=donor   line=cohort median 		11.8 11.8 29.1%
2 S100A9 protein_coding 12.5
bar=donor   line=cohort median 		13.1 13.1 9.9%
3 IL1B protein_coding 5.4
bar=donor   line=cohort median 		6.9 6.9 2.4%
4 CXCL8 protein_coding 6.8
bar=donor   line=cohort median 		7.6 7.6 27.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.7
bar=donor   line=cohort median 		4.0 4.0 91.4%
6 FCGR3B protein_coding 11.0
bar=donor   line=cohort median 		11.3 11.3 25.7%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.8
bar=donor   line=cohort median 		10.9 10.9 43.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.1
bar=donor   line=cohort median 		5.3 5.3 32.5%
9 CD3E protein_coding 2.5
bar=donor   line=cohort median 		2.6 2.6 42.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.4
bar=donor   line=cohort median 		6.3 6.3 57.2%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.7
bar=donor   line=cohort median 		3.4 3.4 62.0%
12 GNLY protein_coding 5.2
bar=donor   line=cohort median 		4.9 4.9 70.9%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.4
bar=donor   line=cohort median 		6.6 6.6 22.3%
14 HBA1 protein_coding 1.3
bar=donor   line=cohort median 		2.6 2.6 34.6%
15 HBA2 protein_coding 4.7
bar=donor   line=cohort median 		5.6 5.6 40.1%
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