GSM5528619

Dataset: gse182409 • Sample: T123 • Status: Pregnancy-stage cohort
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Quality Control Metrics

76,660,431 Total counts Group median: 70,855,220 • 62.0%ile (≈ Median)
32,373 Detected genes Group median: 31,576 • 69.5%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 96.2%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

55.5Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.14
bar=donor   line=cohort median 		9.31 36.2%
CETP Lipid Metabolism 0.65
bar=donor   line=cohort median 		1.18 14.8%
SIRT6 Sirtuin Family 2.61
bar=donor   line=cohort median 		2.22 92.8%
SIRT1 Sirtuin Family 5.50
bar=donor   line=cohort median 		5.50 50.0%
SIRT3 Sirtuin Family 2.58
bar=donor   line=cohort median 		2.33 85.9%
IGF1R Insulin/IGF-1 Signaling 7.01
bar=donor   line=cohort median 		7.09 41.7%
KLOTHO Anti-aging 1.06
bar=donor   line=cohort median 		0.66 74.1%
IRS2 Insulin/IGF-1 Signaling 6.84
bar=donor   line=cohort median 		5.59 98.3%
TP53 Tumor Suppression 2.41
bar=donor   line=cohort median 		2.72 32.1%
SHC1 Signal Transduction 3.82
bar=donor   line=cohort median 		3.95 28.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.7 3,536,845
2 ENSG00000258486 ENSG00000258486 15.6 3,265,430
3 7SK ENSG00000202198 misc_RNA 14.8 1,931,105
4 MALAT1 ENSG00000251562 lncRNA 13.6 804,584
5 ALAS2 ENSG00000158578 protein_coding 13.2 635,085
6 AL355075.4 ENSG00000259001 lncRNA 13.2 604,496
7 S100A9 ENSG00000163220 protein_coding 13.1 583,216
8 SLC25A37 ENSG00000147454 protein_coding 12.9 513,472
9 EPB41 ENSG00000159023 protein_coding 12.9 504,493
10 B2M ENSG00000166710 protein_coding 12.9 499,358

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.9
bar=donor   line=cohort median 		11.8 11.8 52.4%
2 S100A9 protein_coding 13.1
bar=donor   line=cohort median 		13.1 13.1 50.3%
3 IL1B protein_coding 6.4
bar=donor   line=cohort median 		6.9 6.9 24.3%
4 CXCL8 protein_coding 8.9
bar=donor   line=cohort median 		7.6 7.6 91.4%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.7
bar=donor   line=cohort median 		4.0 4.0 68.2%
6 FCGR3B protein_coding 10.8
bar=donor   line=cohort median 		11.3 11.3 17.5%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.5
bar=donor   line=cohort median 		10.9 10.9 90.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.4
bar=donor   line=cohort median 		5.3 5.3 62.7%
9 CD3E protein_coding 2.7
bar=donor   line=cohort median 		2.6 2.6 55.1%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.7
bar=donor   line=cohort median 		6.3 6.3 75.0%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.4
bar=donor   line=cohort median 		3.4 3.4 85.3%
12 GNLY protein_coding 5.2
bar=donor   line=cohort median 		4.9 4.9 67.5%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 8.4
bar=donor   line=cohort median 		6.6 6.6 72.9%
14 HBA1 protein_coding 5.1
bar=donor   line=cohort median 		2.6 2.6 77.1%
15 HBA2 protein_coding 8.2
bar=donor   line=cohort median 		5.6 5.6 77.7%
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