GSM5528621

Dataset: gse182409 • Sample: T125 • Status: Pregnancy-stage cohort
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Quality Control Metrics

64,213,092 Total counts Group median: 70,855,220 • 31.2%ile (≈ Median)
29,655 Detected genes Group median: 31,576 • 33.2%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 57.9%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

69.0Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 10.03
bar=donor   line=cohort median 		9.31 92.1%
CETP Lipid Metabolism 0.85
bar=donor   line=cohort median 		1.18 25.9%
SIRT6 Sirtuin Family 2.92
bar=donor   line=cohort median 		2.22 99.0%
SIRT1 Sirtuin Family 5.59
bar=donor   line=cohort median 		5.50 67.2%
SIRT3 Sirtuin Family 2.40
bar=donor   line=cohort median 		2.33 61.0%
IGF1R Insulin/IGF-1 Signaling 7.22
bar=donor   line=cohort median 		7.09 66.6%
KLOTHO Anti-aging 0.57
bar=donor   line=cohort median 		0.66 41.7%
IRS2 Insulin/IGF-1 Signaling 6.49
bar=donor   line=cohort median 		5.59 96.9%
TP53 Tumor Suppression 2.91
bar=donor   line=cohort median 		2.72 62.4%
SHC1 Signal Transduction 4.16
bar=donor   line=cohort median 		3.95 76.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.7 1,657,829
2 7SK ENSG00000202198 misc_RNA 13.9 937,557
3 ENSG00000258486 ENSG00000258486 13.9 926,826
4 ALAS2 ENSG00000158578 protein_coding 13.4 678,220
5 MALAT1 ENSG00000251562 lncRNA 13.4 676,893
6 B2M ENSG00000166710 protein_coding 13.2 601,636
7 SLC25A37 ENSG00000147454 protein_coding 12.9 461,025
8 AL355075.4 ENSG00000259001 lncRNA 12.8 449,454
9 EPB41 ENSG00000159023 protein_coding 12.7 402,501
10 ENSG00000266037 ENSG00000266037 12.5 373,007

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.2
bar=donor   line=cohort median 		11.8 11.8 12.7%
2 S100A9 protein_coding 12.4
bar=donor   line=cohort median 		13.1 13.1 5.8%
3 IL1B protein_coding 7.4
bar=donor   line=cohort median 		6.9 6.9 85.3%
4 CXCL8 protein_coding 7.6
bar=donor   line=cohort median 		7.6 7.6 51.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.7
bar=donor   line=cohort median 		4.0 4.0 41.4%
6 FCGR3B protein_coding 11.0
bar=donor   line=cohort median 		11.3 11.3 22.3%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.7
bar=donor   line=cohort median 		10.9 10.9 31.2%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.2
bar=donor   line=cohort median 		5.3 5.3 38.7%
9 CD3E protein_coding 1.7
bar=donor   line=cohort median 		2.6 2.6 12.0%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.6
bar=donor   line=cohort median 		6.3 6.3 74.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.9
bar=donor   line=cohort median 		3.4 3.4 21.6%
12 GNLY protein_coding 4.7
bar=donor   line=cohort median 		4.9 4.9 40.1%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.1
bar=donor   line=cohort median 		6.6 6.6 16.1%
14 HBA1 protein_coding 2.6
bar=donor   line=cohort median 		2.6 2.6 50.3%
15 HBA2 protein_coding 5.6
bar=donor   line=cohort median 		5.6 5.6 49.0%
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