GSM5528622

Dataset: gse182409 • Sample: T126 • Status: Pregnancy-stage cohort
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Quality Control Metrics

82,990,970 Total counts Group median: 70,855,220 • 77.1%ile (↑ High)
32,080 Detected genes Group median: 31,576 • 62.0%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 3.1%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

47.6Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.70
bar=donor   line=cohort median 		9.31 81.0%
CETP Lipid Metabolism 1.31
bar=donor   line=cohort median 		1.18 59.0%
SIRT6 Sirtuin Family 2.26
bar=donor   line=cohort median 		2.22 55.5%
SIRT1 Sirtuin Family 5.57
bar=donor   line=cohort median 		5.50 64.5%
SIRT3 Sirtuin Family 2.44
bar=donor   line=cohort median 		2.33 70.0%
IGF1R Insulin/IGF-1 Signaling 6.77
bar=donor   line=cohort median 		7.09 21.0%
KLOTHO Anti-aging -0.91
bar=donor   line=cohort median 		0.66 1.0%
IRS2 Insulin/IGF-1 Signaling 4.98
bar=donor   line=cohort median 		5.59 12.1%
TP53 Tumor Suppression 2.40
bar=donor   line=cohort median 		2.72 31.4%
SHC1 Signal Transduction 4.19
bar=donor   line=cohort median 		3.95 80.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000258486 ENSG00000258486 15.8 4,035,760
2 7SK ENSG00000202198 misc_RNA 15.4 3,011,163
3 ENSG00000265150 ENSG00000265150 15.3 2,805,093
4 AL355075.4 ENSG00000259001 lncRNA 14.2 1,280,543
5 B2M ENSG00000166710 protein_coding 13.8 1,017,494
6 S100A9 ENSG00000163220 protein_coding 13.8 972,481
7 MALAT1 ENSG00000251562 lncRNA 13.2 641,181
8 NAMPT ENSG00000105835 protein_coding 13.1 600,417
9 SOD2 ENSG00000112096 protein_coding 12.9 530,078
10 EEF1A1 ENSG00000156508 protein_coding 12.6 420,659

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.4
bar=donor   line=cohort median 		11.8 11.8 90.1%
2 S100A9 protein_coding 13.8
bar=donor   line=cohort median 		13.1 13.1 94.2%
3 IL1B protein_coding 7.8
bar=donor   line=cohort median 		6.9 6.9 96.2%
4 CXCL8 protein_coding 8.2
bar=donor   line=cohort median 		7.6 7.6 76.4%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.1
bar=donor   line=cohort median 		4.0 4.0 79.1%
6 FCGR3B protein_coding 11.8
bar=donor   line=cohort median 		11.3 11.3 83.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.2
bar=donor   line=cohort median 		10.9 10.9 71.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.3
bar=donor   line=cohort median 		5.3 5.3 52.4%
9 CD3E protein_coding 1.7
bar=donor   line=cohort median 		2.6 2.6 12.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.4
bar=donor   line=cohort median 		6.3 6.3 58.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.1
bar=donor   line=cohort median 		3.4 3.4 32.5%
12 GNLY protein_coding 4.9
bar=donor   line=cohort median 		4.9 4.9 53.1%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 8.9
bar=donor   line=cohort median 		6.6 6.6 75.7%
14 HBA1 protein_coding 1.7
bar=donor   line=cohort median 		2.6 2.6 39.4%
15 HBA2 protein_coding 5.3
bar=donor   line=cohort median 		5.6 5.6 44.9%
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