GSM5528623

Dataset: gse182409 • Sample: T127 • Status: Pregnancy-stage cohort
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Quality Control Metrics

75,760,719 Total counts Group median: 70,855,220 • 59.9%ile (≈ Median)
28,944 Detected genes Group median: 31,576 • 26.4%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 68.8%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

38.1Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.86
bar=donor   line=cohort median 		9.31 16.9%
CETP Lipid Metabolism 0.87
bar=donor   line=cohort median 		1.18 28.6%
SIRT6 Sirtuin Family 1.96
bar=donor   line=cohort median 		2.22 20.3%
SIRT1 Sirtuin Family 5.75
bar=donor   line=cohort median 		5.50 92.1%
SIRT3 Sirtuin Family 2.23
bar=donor   line=cohort median 		2.33 31.4%
IGF1R Insulin/IGF-1 Signaling 7.00
bar=donor   line=cohort median 		7.09 40.3%
KLOTHO Anti-aging 1.13
bar=donor   line=cohort median 		0.66 79.7%
IRS2 Insulin/IGF-1 Signaling 5.32
bar=donor   line=cohort median 		5.59 27.9%
TP53 Tumor Suppression 1.98
bar=donor   line=cohort median 		2.72 10.0%
SHC1 Signal Transduction 3.84
bar=donor   line=cohort median 		3.95 34.1%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.3 1,611,808
2 ENSG00000258486 ENSG00000258486 14.1 1,370,117
3 ENSG00000265150 ENSG00000265150 14.0 1,240,084
4 B2M ENSG00000166710 protein_coding 13.3 777,653
5 MALAT1 ENSG00000251562 lncRNA 13.1 687,656
6 S100A9 ENSG00000163220 protein_coding 12.9 579,104
7 AL355075.4 ENSG00000259001 lncRNA 12.8 570,850
8 EEF1A1 ENSG00000156508 protein_coding 12.6 491,286
9 NAMPT ENSG00000105835 protein_coding 12.5 463,668
10 BNIP3L ENSG00000104765 protein_coding 12.3 394,648

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.7
bar=donor   line=cohort median 		11.8 11.8 40.1%
2 S100A9 protein_coding 12.9
bar=donor   line=cohort median 		13.1 13.1 33.9%
3 IL1B protein_coding 6.7
bar=donor   line=cohort median 		6.9 6.9 40.1%
4 CXCL8 protein_coding 8.6
bar=donor   line=cohort median 		7.6 7.6 86.6%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.7
bar=donor   line=cohort median 		4.0 4.0 40.1%
6 FCGR3B protein_coding 11.0
bar=donor   line=cohort median 		11.3 11.3 22.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.2
bar=donor   line=cohort median 		10.9 10.9 70.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.8
bar=donor   line=cohort median 		5.3 5.3 91.4%
9 CD3E protein_coding 2.2
bar=donor   line=cohort median 		2.6 2.6 29.1%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 7.0
bar=donor   line=cohort median 		6.3 6.3 91.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.9
bar=donor   line=cohort median 		3.4 3.4 22.9%
12 GNLY protein_coding 4.0
bar=donor   line=cohort median 		4.9 4.9 9.2%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.4
bar=donor   line=cohort median 		6.6 6.6 21.6%
14 HBA1 protein_coding 1.4
bar=donor   line=cohort median 		2.6 2.6 36.0%
15 HBA2 protein_coding 4.4
bar=donor   line=cohort median 		5.6 5.6 35.3%
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