GSM5528625

Dataset: gse182409 • Sample: T129 • Status: Pregnancy-stage cohort
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Quality Control Metrics

52,744,157 Total counts Group median: 70,855,220 • 12.0%ile (↓ Low)
27,537 Detected genes Group median: 31,576 • 10.6%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 52.4%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

50.1Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.57
bar=donor   line=cohort median 		9.31 4.5%
CETP Lipid Metabolism 1.26
bar=donor   line=cohort median 		1.18 54.8%
SIRT6 Sirtuin Family 2.44
bar=donor   line=cohort median 		2.22 79.7%
SIRT1 Sirtuin Family 5.75
bar=donor   line=cohort median 		5.50 91.4%
SIRT3 Sirtuin Family 2.32
bar=donor   line=cohort median 		2.33 48.6%
IGF1R Insulin/IGF-1 Signaling 6.78
bar=donor   line=cohort median 		7.09 22.4%
KLOTHO Anti-aging 0.86
bar=donor   line=cohort median 		0.66 62.4%
IRS2 Insulin/IGF-1 Signaling 5.67
bar=donor   line=cohort median 		5.59 56.9%
TP53 Tumor Suppression 2.67
bar=donor   line=cohort median 		2.72 47.2%
SHC1 Signal Transduction 3.84
bar=donor   line=cohort median 		3.95 33.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.2 944,953
2 ENSG00000265150 ENSG00000265150 14.0 821,591
3 ENSG00000258486 ENSG00000258486 13.9 790,243
4 MALAT1 ENSG00000251562 lncRNA 13.3 519,051
5 ALAS2 ENSG00000158578 protein_coding 13.2 491,700
6 B2M ENSG00000166710 protein_coding 13.1 448,461
7 S100A9 ENSG00000163220 protein_coding 13.0 425,836
8 AL355075.4 ENSG00000259001 lncRNA 12.7 353,752
9 EPB41 ENSG00000159023 protein_coding 12.6 312,478
10 SLC25A37 ENSG00000147454 protein_coding 12.5 307,372

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.7
bar=donor   line=cohort median 		11.8 11.8 42.8%
2 S100A9 protein_coding 13.0
bar=donor   line=cohort median 		13.1 13.1 42.1%
3 IL1B protein_coding 6.7
bar=donor   line=cohort median 		6.9 6.9 43.5%
4 CXCL8 protein_coding 7.7
bar=donor   line=cohort median 		7.6 7.6 54.5%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 6.4
bar=donor   line=cohort median 		4.0 4.0 97.6%
6 FCGR3B protein_coding 11.0
bar=donor   line=cohort median 		11.3 11.3 28.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.3
bar=donor   line=cohort median 		10.9 10.9 79.1%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.1
bar=donor   line=cohort median 		5.3 5.3 21.6%
9 CD3E protein_coding 2.1
bar=donor   line=cohort median 		2.6 2.6 20.9%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.7
bar=donor   line=cohort median 		6.3 6.3 76.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.8
bar=donor   line=cohort median 		3.4 3.4 65.4%
12 GNLY protein_coding 5.2
bar=donor   line=cohort median 		4.9 4.9 70.2%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 6.8
bar=donor   line=cohort median 		6.6 6.6 53.8%
14 HBA1 protein_coding 2.1
bar=donor   line=cohort median 		2.6 2.6 44.2%
15 HBA2 protein_coding 5.7
bar=donor   line=cohort median 		5.6 5.6 51.0%
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