GSM5528626

Dataset: gse182409 • Sample: T130 • Status: Pregnancy-stage cohort

Quality Control Metrics

76,927,203 Total counts Group median: 70,855,220 • 62.7%ile (≈ Median)
31,472 Detected genes Group median: 31,576 • 48.3%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 40.8%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

61.5Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.66
bar=donor   line=cohort median
9.31 76.9%
CETP Lipid Metabolism 1.20
bar=donor   line=cohort median
1.18 52.8%
SIRT6 Sirtuin Family 2.45
bar=donor   line=cohort median
2.22 81.7%
SIRT1 Sirtuin Family 5.51
bar=donor   line=cohort median
5.50 53.5%
SIRT3 Sirtuin Family 2.51
bar=donor   line=cohort median
2.33 76.9%
IGF1R Insulin/IGF-1 Signaling 7.19
bar=donor   line=cohort median
7.09 59.7%
KLOTHO Anti-aging 1.13
bar=donor   line=cohort median
0.66 79.0%
IRS2 Insulin/IGF-1 Signaling 5.78
bar=donor   line=cohort median
5.59 65.2%
TP53 Tumor Suppression 2.25
bar=donor   line=cohort median
2.72 23.1%
SHC1 Signal Transduction 3.91
bar=donor   line=cohort median
3.95 45.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000258486 ENSG00000258486 15.6 3,076,249
2 ENSG00000265150 ENSG00000265150 15.5 2,858,369
3 7SK ENSG00000202198 misc_RNA 14.5 1,461,693
4 ALAS2 ENSG00000158578 protein_coding 13.7 809,546
5 AL355075.4 ENSG00000259001 lncRNA 13.6 763,680
6 MALAT1 ENSG00000251562 lncRNA 13.5 721,261
7 B2M ENSG00000166710 protein_coding 13.5 710,089
8 BNIP3L ENSG00000104765 protein_coding 13.0 499,622
9 NAMPT ENSG00000105835 protein_coding 12.9 484,220
10 EPB41 ENSG00000159023 protein_coding 12.9 474,270

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.6
bar=donor   line=cohort median
11.8 11.8 34.6%
2 S100A9 protein_coding 12.9
bar=donor   line=cohort median
13.1 13.1 32.5%
3 IL1B protein_coding 6.9
bar=donor   line=cohort median
6.9 6.9 55.1%
4 CXCL8 protein_coding 8.9
bar=donor   line=cohort median
7.6 7.6 90.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 2.6
bar=donor   line=cohort median
4.0 4.0 13.4%
6 FCGR3B protein_coding 11.6
bar=donor   line=cohort median
11.3 11.3 69.5%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.1
bar=donor   line=cohort median
10.9 10.9 66.1%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 4.7
bar=donor   line=cohort median
5.3 5.3 5.1%
9 CD3E protein_coding 1.4
bar=donor   line=cohort median
2.6 2.6 4.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.0
bar=donor   line=cohort median
6.3 6.3 29.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.5
bar=donor   line=cohort median
3.4 3.4 11.3%
12 GNLY protein_coding 4.0
bar=donor   line=cohort median
4.9 4.9 10.6%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 7.2
bar=donor   line=cohort median
6.6 6.6 56.5%
14 HBA1 protein_coding 2.6
bar=donor   line=cohort median
2.6 2.6 49.7%
15 HBA2 protein_coding 4.9
bar=donor   line=cohort median
5.6 5.6 41.4%