GSM5528627

Dataset: gse182409 • Sample: T131 • Status: Pregnancy-stage cohort
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Quality Control Metrics

91,158,455 Total counts Group median: 70,855,220 • 91.4%ile (↑ High)
31,691 Detected genes Group median: 31,576 • 52.4%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 14.7%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

45.9Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 10.20
bar=donor   line=cohort median 		9.31 95.5%
CETP Lipid Metabolism 0.36
bar=donor   line=cohort median 		1.18 6.6%
SIRT6 Sirtuin Family 2.26
bar=donor   line=cohort median 		2.22 56.2%
SIRT1 Sirtuin Family 5.92
bar=donor   line=cohort median 		5.50 98.3%
SIRT3 Sirtuin Family 1.83
bar=donor   line=cohort median 		2.33 1.7%
IGF1R Insulin/IGF-1 Signaling 7.39
bar=donor   line=cohort median 		7.09 80.3%
KLOTHO Anti-aging 0.16
bar=donor   line=cohort median 		0.66 19.7%
IRS2 Insulin/IGF-1 Signaling 5.86
bar=donor   line=cohort median 		5.59 74.8%
TP53 Tumor Suppression 1.95
bar=donor   line=cohort median 		2.72 7.2%
SHC1 Signal Transduction 3.76
bar=donor   line=cohort median 		3.95 18.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.9 2,451,759
2 ENSG00000258486 ENSG00000258486 14.8 2,170,261
3 7SK ENSG00000202198 misc_RNA 14.4 1,725,249
4 S100A9 ENSG00000163220 protein_coding 13.8 1,119,770
5 B2M ENSG00000166710 protein_coding 13.6 948,269
6 AL355075.4 ENSG00000259001 lncRNA 13.1 706,238
7 NAMPT ENSG00000105835 protein_coding 13.0 660,039
8 MALAT1 ENSG00000251562 lncRNA 12.9 616,125
9 BNIP3L ENSG00000104765 protein_coding 12.8 545,326
10 SOD2 ENSG00000112096 protein_coding 12.6 493,539

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.6
bar=donor   line=cohort median 		11.8 11.8 96.2%
2 S100A9 protein_coding 13.8
bar=donor   line=cohort median 		13.1 13.1 96.2%
3 IL1B protein_coding 7.4
bar=donor   line=cohort median 		6.9 6.9 88.0%
4 CXCL8 protein_coding 8.6
bar=donor   line=cohort median 		7.6 7.6 86.0%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 6.3
bar=donor   line=cohort median 		4.0 4.0 96.2%
6 FCGR3B protein_coding 10.8
bar=donor   line=cohort median 		11.3 11.3 16.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.5
bar=donor   line=cohort median 		10.9 10.9 92.1%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.0
bar=donor   line=cohort median 		5.3 5.3 20.9%
9 CD3E protein_coding 1.3
bar=donor   line=cohort median 		2.6 2.6 1.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.6
bar=donor   line=cohort median 		6.3 6.3 7.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.9
bar=donor   line=cohort median 		3.4 3.4 20.9%
12 GNLY protein_coding 4.8
bar=donor   line=cohort median 		4.9 4.9 41.4%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.7
bar=donor   line=cohort median 		6.6 6.6 29.1%
14 HBA1 protein_coding 0.2
bar=donor   line=cohort median 		2.6 2.6 22.9%
15 HBA2 protein_coding 3.4
bar=donor   line=cohort median 		5.6 5.6 25.0%
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