GSM5528628

Dataset: gse182409 • Sample: T132 • Status: Pregnancy-stage cohort
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Quality Control Metrics

91,897,373 Total counts Group median: 70,855,220 • 92.8%ile (↑ High)
33,332 Detected genes Group median: 31,576 • 88.0%ile (↑ High)
0 Mitochondrial fraction (%) Group median: 0 • 57.2%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

37.9Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.04
bar=donor   line=cohort median 		9.31 26.6%
CETP Lipid Metabolism 0.24
bar=donor   line=cohort median 		1.18 4.5%
SIRT6 Sirtuin Family 2.13
bar=donor   line=cohort median 		2.22 41.7%
SIRT1 Sirtuin Family 5.71
bar=donor   line=cohort median 		5.50 87.9%
SIRT3 Sirtuin Family 2.22
bar=donor   line=cohort median 		2.33 30.0%
IGF1R Insulin/IGF-1 Signaling 6.86
bar=donor   line=cohort median 		7.09 26.6%
KLOTHO Anti-aging 1.47
bar=donor   line=cohort median 		0.66 94.8%
IRS2 Insulin/IGF-1 Signaling 5.58
bar=donor   line=cohort median 		5.59 46.6%
TP53 Tumor Suppression 1.81
bar=donor   line=cohort median 		2.72 3.1%
SHC1 Signal Transduction 3.74
bar=donor   line=cohort median 		3.95 16.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.6 2,149,045
2 ENSG00000258486 ENSG00000258486 14.5 2,031,050
3 7SK ENSG00000202198 misc_RNA 14.5 1,895,373
4 S100A9 ENSG00000163220 protein_coding 13.9 1,258,912
5 B2M ENSG00000166710 protein_coding 13.6 1,054,863
6 MALAT1 ENSG00000251562 lncRNA 13.5 951,018
7 AL355075.4 ENSG00000259001 lncRNA 13.1 723,871
8 NAMPT ENSG00000105835 protein_coding 13.0 713,552
9 S100A8 ENSG00000143546 protein_coding 12.7 565,482
10 SORL1 ENSG00000137642 protein_coding 12.6 518,480

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.7
bar=donor   line=cohort median 		11.8 11.8 98.3%
2 S100A9 protein_coding 13.9
bar=donor   line=cohort median 		13.1 13.1 97.6%
3 IL1B protein_coding 7.5
bar=donor   line=cohort median 		6.9 6.9 91.4%
4 CXCL8 protein_coding 7.6
bar=donor   line=cohort median 		7.6 7.6 51.0%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 4.0
bar=donor   line=cohort median 		4.0 4.0 48.3%
6 FCGR3B protein_coding 11.8
bar=donor   line=cohort median 		11.3 11.3 79.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.9
bar=donor   line=cohort median 		10.9 10.9 50.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.3
bar=donor   line=cohort median 		5.3 5.3 53.8%
9 CD3E protein_coding 2.2
bar=donor   line=cohort median 		2.6 2.6 31.2%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.5
bar=donor   line=cohort median 		6.3 6.3 5.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 2.9
bar=donor   line=cohort median 		3.4 3.4 20.2%
12 GNLY protein_coding 5.3
bar=donor   line=cohort median 		4.9 4.9 79.8%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 4.1
bar=donor   line=cohort median 		6.6 6.6 1.0%
14 HBA1 protein_coding 0.3
bar=donor   line=cohort median 		2.6 2.6 24.3%
15 HBA2 protein_coding 3.3
bar=donor   line=cohort median 		5.6 5.6 22.3%
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